ArticleDiabetes care2019
hs-CRP Is Associated With Incident Diabetic Nephropathy: Findings From the Jackson Heart Study.
Article in Diabetes care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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Who cites it
26 citing papers in PubMed, 48 citations in OpenAlex.
- Healthy diet and slower biological aging as protective factors against microvascular complications in type 2 diabetes.GeroScience · 2026Article
- Monocyte dipeptidyl peptidase 4 activity is associated with urinary albumin excretion in type 2 diabetes.Journal of diabetes investigation · 2026Article
- Association between serum carbohydrate antigen 199 levels and diabetic kidney disease in patients with type 2 diabetes: a retrospective cross-sectional study from Northwest China.BMC endocrine disorders · 2026Article
- Stroke Incidence and High-Sensitivity C-Reactive Protein Among African Americans: The Jackson Heart Study.Ethnicity & disease · 2025Article
- Article
- Beat-to-Beat Blood Pressure Variability Within 24 Hours of Ischemic Stroke Onset: A Potential Predictor of Functional Prognosis.Journal of the American Heart Association · 2024Article
- Association between glucose levels and all-cause mortality in cancer survivors: findings from NHANES 1999-2018.BMC public health · 2024Article
- Mendelian randomization analysis reveals causal factors behind diabetic nephropathy: evidence, opportunities, and challenges.Frontiers in endocrinology · 2024Review
- Association of systemic immune-inflammation index with all-cause and cardio-cerebrovascular mortality in individuals with diabetic kidney disease: evidence from NHANES 1999-2018.Frontiers in endocrinology · 2024Article
- FTO fuels diabetes-induced vascular endothelial dysfunction associated with inflammation by erasing m6A methylation of TNIP1.The Journal of clinical investigation · 2023Article
- Effects of Niaoduqing granules on inflammatory response of diabetic kidney disease: A meta‑analysis.Experimental and therapeutic medicine · 2023Article
- Prevalence and influencing factors of hyperuricemia in middle-aged and older adults in the Yao minority area of China: a cross-sectional study.Scientific reports · 2023Article
- Effects of sleep duration and changes in body mass index on diabetic kidney disease: a prospective cohort study.Frontiers in endocrinology · 2023Article
- Compositional analysis of movement behaviors' association on high-sensitivity c-reactive protein: the Jackson heart study.Annals of epidemiology · 2022Article
- The Anti-Inflammatory Effect of Novel Antidiabetic Agents.Life (Basel, Switzerland) · 2022Review
- Role of High-Sensitivity C-reactive Protein (Hs-CRP) in Non-communicable Diseases: A Review.Cureus · 2022Review
- Etiopathogenesis of kidney disease in minority populations and an updated special focus on treatment in diabetes and hypertension.Journal of the National Medical Association · 2022Review
- Anti-inflammatory effect of SGLT-2 inhibitors via uric acid and insulin.Cellular and molecular life sciences : CMLS · 2022Article
- Obesity and CKD in Sub-Saharan Africa: A Narrative Review.Kidney medicine · 2022Review
- Novel glucose-responsive nanoparticles based on p-hydroxyphenethyl anisate and 3-acrylamidophenylboronic acid reduce blood glucose and ameliorate diabetic nephropathy.Materials today. Bio · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveAfrican Americans (AA) suffer disproportionately from diabetic nephropathy (DN). C-reactive protein (CRP) has been associated with prevalent DN, but its association with incident DN in AA is unknown. We examined hs-CRP and incident DN in AA. RESEARCH DESIGN AND
methodsWe conducted a longitudinal analysis of data from exams 1, 2, and 3 in 4,043 eligible Jackson Heart Study (JHS) participants. Participants with DN or without hs-CRP at exam 1 were excluded. Incident DN was defined as urinary albumin-to-creatinine ratio (ACR) >30 mg/g or self-reported dialysis/transplantation and type 2 diabetes mellitus (DM) or HbA
resultsDuring 7.8 years of median follow-up time, participants who developed DN had significantly higher baseline hs-CRP, age, fasting glucose, triglycerides, ACR, systolic blood pressure, waist circumference, and duration of DM (
conclusionsInflammation, as measured by hs-CRP levels, may be associated with incident DN in AA. Further studies are warranted to replicate and elucidate the basis for this association.
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Registered trials
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