Evidence map›Paper›PMID 31511228›Full record

ArticleBlood advances2019

Allogeneic hematopoietic stem cell transplant for relapsed and refractory non-Hodgkin lymphoma in pediatric patients.

Swati Naik, Caridad A Martinez, Bilal Omer, Ghadir Sasa, Khaled Yassine, Carl E Allen, Kala Kamdar, Robert Orth, Mengfen Wu, Kathryn Leung and 4 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Swati NaikCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Caridad A MartinezCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Bilal OmerCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Ghadir SasaCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Khaled YassineCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Carl E AllenCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Kala KamdarTexas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
Robert OrthDepartment of Pediatrics, Baylor College of Medicine, Houston, TX.
Mengfen WuBiostatistics Shared Resource, Dan L. Duncan Center, and.
Kathryn LeungCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Stephen GottschalkCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Malcolm K BrennerCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Helen E HeslopCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Robert A KranceCenter for Cell and Gene Therapy, Texas Children's Hospital/Baylor College of Medicine/Houston Methodist Hospital, Houston, TX.
Baylor College of Medicine · USHouston Methodist · USMethodist Hospital · USChildren's Cancer Center · USTexas Children's Hospital · US

Funding

PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAMK12CA090433 · NCI · BAYLOR COLLEGE OF MEDICINE · PI CARL E ALLEN, Donald W. Parsons · 2002 to 2026
$18.5M
NCI NIH HHS K12 CA090433
6 · The paper itself

Abstract

Allogeneic hematopoietic stem cell transplant (HSCT) for relapsed pediatric non-Hodgkin lymphoma (NHL) is often reserved for patients with certain NHL subtypes or high-risk disease whereas the remainder receive autologous HSCT. Given the aggressive nature of pediatric NHL, we performed allogeneic HSCTs for all patients regardless of disease risk. We report overall survival (OS) and prognostic variables in 36 pediatric patients who underwent allogeneic HSCT between 1998 and 2016. OS at 3 years was 67%. The 3-year OS varied based on NHL subtype: 100% for anaplastic large cell lymphoma (n = 14), 63% for diffuse large B-cell lymphoma (n = 8), 17% for lymphoblastic lymphoma (LL; n = 9) and 80% for other subtypes combined (n = 5). Disease status influenced outcome with 3-year OS of 100% for patients in complete remission (n = 15), 59% with partial remission (PR; n = 17), and 0% with progressive/stable disease (n = 3) (

Indexed as

AdolescentAdultChildChild, PreschoolFemaleHematopoietic Stem Cell TransplantationHumansLymphoma, Non-HodgkinMaleRecurrenceRetrospective StudiesTransplantation ConditioningTransplantation, HomologousTreatment OutcomeYoung Adult

Identifiers

PMID31511228
PMCPMC6759733
OpenAlexW2972834279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.