Evidence map›Paper›PMID 31510846›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2019

Early Alterations of Endothelial Nitric Oxide Synthase Expression Patterns in the Guinea Pig Cochlea After Noise Exposure.

Ulf R Heinrich, Irene Schmidtmann, Regina Meuser, Benjamin P Ernst, Desiree Wünsch, Svenja Siemer, Alena Gribko, Roland H Stauber, Sebastian Strieth

Open access · bronzeAbstract read
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Effects of Nitric Oxide Expression on Hearing Loss.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Review
  4. Regulation of Endothelial Nitric Oxide Synthase in the Reticular Lamina of the Organ of Corti by a Nitric Oxide Donor.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ulf R HeinrichDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.
Irene SchmidtmannInstitute for Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center Mainz, Mainz, Germany.
Regina MeuserInstitute for Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center Mainz, Mainz, Germany.
Benjamin P ErnstDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.
Desiree WünschDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.
Svenja SiemerDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.
Alena GribkoDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.
Roland H StauberDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.
Sebastian StriethDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.
University Medical Center of the Johannes Gutenberg University Mainz · DEJohannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Constitutively expressed endothelial nitric oxide synthase (eNOS) is supposed to play a role in noise-induced nitric oxide (NO)-production. It is commonly known that intense noise exposure results in inducible NOS (iNOS) expression and increased NO-production, but knowledge about a contribution of the eNOS isoform is still lacking. Effects of noise exposure on eNOS immunolabeling were determined in male guinea pigs (

Indexed as

AnimalsCochleaGuinea PigsHearing Loss, Noise-InducedImmunohistochemistryMaleNitric Oxide Synthase Type IIINoiseNitric Oxide Synthase Type IIIeNOSNOnoise-induced hearing loss (NIHL)otoprotectionreticular lamina

Identifiers

PMID31510846
PMCPMC6824004
OpenAlexW2972801279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.