ArticleOptics express2019
Microrheological quantification of viscoelastic properties with photonic force optical coherence elastography.
Article in Optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Recent advances in optical elastography and emerging opportunities in the basic sciences and translational medicine [Invited].Biomedical optics express · 2023Review
- Light-sheet photonic force optical coherence elastography for high-throughput quantitative 3D micromechanical imaging.Nature communications · 2022Article
- Introduction to optical coherence elastography: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2022Article
- Valve endothelial-interstitial interactions drive emergent complex calcific lesion formation in vitro.Biomaterials · 2021Article
- Advances in Doppler optical coherence tomography and angiography.Translational biophotonics · 2019Article
- Spectroscopic photonic force optical coherence elastography.Optics letters · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Photonic force optical coherence elastography (PF-OCE) is a new approach for volumetric characterization of microscopic mechanical properties of three-dimensional viscoelastic medium. It is based on measurements of the complex mechanical response of embedded micro-beads to harmonically modulated radiation-pressure force from a weakly-focused beam. Here, we utilize the Generalized Stokes-Einstein relation to reconstruct local complex shear modulus in polyacrylamide gels by combining PF-OCE measurements of bead mechanical responses and experimentally measured depth-resolved radiation-pressure force profile of our forcing beam. Data exclusion criteria for quantitative PF-OCE based on three noise-related parameters were identified from the analysis of measurement noise at key processing steps. Shear storage modulus measured by quantitative PF-OCE was found to be in good agreement with standard shear rheometry, whereas shear loss modulus was in agreement with previously published atomic force microscopy results. The analysis and results presented here may serve to inform practical, application-specific implementations of PF-OCE, and establish the technique as a viable tool for quantitative mechanical microscopy.
Identifiers
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Registered trials
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