Evidence map›Paper›PMID 31510010›Full record

ArticleInternational journal of molecular sciences2019

A Novel Tanshinone Analog Exerts Anti-Cancer Effects in Prostate Cancer by Inducing Cell Apoptosis, Arresting Cell Cycle at G2 Phase and Blocking Metastatic Ability.

Mengling Wang, Xueyi Zeng, Shengyou Li, Zekun Sun, Jia Yu, Chao Chen, Xiangchun Shen, Weidong Pan, Heng Luo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A review of tanshinone compounds in prostate cancer treatment.Translational andrology and urology · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Frontiers in pharmacology · 2022
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mengling WangState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Xueyi ZengState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Shengyou LiKey Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Zekun SunKey Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Jia YuState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Chao ChenState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.ORCID 0000-0002-0378-0589
Xiangchun ShenState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Weidong PanState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China. panweidong@gzcnp.cn.
Heng LuoState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China. luoheng@gzcnp.cn.ORCID 0000-0003-3418-5739
Guiyang Medical University · CNGuizhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa), an epithelial malignant tumor, is the second common cause of cancer death among males in western countries. Thus, the development of new strategies is urgently needed. Tanshinones isolated from

Indexed as

AbietanesAnimalsAntineoplastic Agents, PhytogenicApoptosisApoptosis Regulatory ProteinsCell Line, TumorG2 Phase Cell Cycle CheckpointsHumansMaleMice, Inbred BALB CMice, NudeNeoplasm MetastasisPhytotherapyProstatic NeoplasmsSalvia miltiorrhizaXenograft Model Antitumor AssaysAbietanesAntineoplastic Agents, PhytogenicApoptosis Regulatory Proteinstanshinonecell apoptosiscell cycle arrestmetastasis potencyprostate cancerquinone analog

Identifiers

PMID31510010
PMCPMC6770861
OpenAlexW2972513210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.