Evidence map›Paper›PMID 31509995›Full record

ArticleAntioxidants (Basel, Switzerland)2019

A Delphinidin-Enriched Maqui Berry Extract Improves Bone Metabolism and Protects against Bone Loss in Osteopenic Mouse Models.

Masahiro Nagaoka, Toyonobu Maeda, Masahiro Chatani, Kazuaki Handa, Tomoyuki Yamakawa, Shuichi Kiyohara, Takako Negishi-Koga, Yasumasa Kato, Masamichi Takami, Shumpei Niida and 3 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Therapeutic Efficacy of Medicinal Plants with Allopathic Medicine in Musculoskeletal Diseases.International journal of plant, animal and environmental sciences · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Experimental biology and medicine (Maywood, N.J.) · 2022
    Article
  12. Article
  13. Article
  14. Anthocyanins, Microbiome and Health Benefits in Aging.Molecules (Basel, Switzerland) · 2021
    Review
  15. Review
  16. Article
  17. Osteoprotective Roles of Green Tea Catechins.Antioxidants (Basel, Switzerland) · 2020
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Masahiro NagaokaDepartment of Pharmacology, School of Dentistry, Ohu University, Fukushima 963-8611, Japan. m-nagaoka@den.ohu-u.ac.jp.
Toyonobu MaedaDepartment of Oral Function and Molecular Biology, School of Dentistry, Ohu University, Fukushima 963-8611, Japan. t-maeda@den.ohu-u.ac.jp.
Masahiro ChataniDepartment of Pharmacology, School of Dentistry, Showa University, Tokyo 142-8551, Japan. chatani@dent.showa-u.ac.jp.
Kazuaki HandaDepartment of Pharmacology, School of Dentistry, Showa University, Tokyo 142-8551, Japan. kazuaki.handa@gmail.com.
Tomoyuki YamakawaDepartment of Pharmacology, School of Dentistry, Showa University, Tokyo 142-8551, Japan. t.yamakawa@med.showa-u.ac.jp.
Shuichi KiyoharaDepartment of Pharmacology, School of Dentistry, Showa University, Tokyo 142-8551, Japan. skiyohara@dent.showa-u.ac.jp.
Takako Negishi-KogaDepartment of Pharmacology, School of Dentistry, Showa University, Tokyo 142-8551, Japan. koga@dent.showa-u.ac.jp.
Yasumasa KatoDepartment of Oral Function and Molecular Biology, School of Dentistry, Ohu University, Fukushima 963-8611, Japan. yasumasa-kato@umin.ac.jp.ORCID 0000-0003-0192-9324
Masamichi TakamiDepartment of Pharmacology, School of Dentistry, Showa University, Tokyo 142-8551, Japan. takami@dent.showa-u.ac.jp.
Shumpei NiidaMedical Genome Center, National Center for Geriatrics and Gerontology (NCGG), Aichi 474-8511, Japan. sniida@ncgg.go.jp.
Stefanie C LangAnklam Extrakt GmbH, Marienbergstr. 92, 90411 Nuremberg, Germany. stefanie.lang@anklam-extrakt.com.
Marlena C KrugerSchool of Health Sciences, College of Health, Massey University, Palmerston North 4442, New Zealand. M.C.Kruger@massey.ac.nz.ORCID 0000-0002-8646-9672
Keiko SuzukiDepartment of Pharmacology, School of Dentistry, Ohu University, Fukushima 963-8611, Japan. kei-suzuki@umin.ac.jp.
Showa University · JPOhu University · JPMassey University · NZNational Center for Geriatrics and Gerontology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In our previous investigation, delphinidin, one of the most abundant anthocyanins found in vegetables and berry fruits, had been shown to inhibit osteoclasts and prevent bone loss in mouse models of osteoporosis. In the present study, we investigated whether a delphinidin glycoside-enriched maqui berry extract (MBE, Delphinol

Indexed as

anthocyaninantioxidantdelphinidinmaqui berryNF-κBosteoblastosteoclastosteopenic mouseoxidative stress

Identifiers

PMID31509995
PMCPMC6769591
OpenAlexW2972746987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.