Evidence map›Paper›PMID 31509957›Full record

ReviewInternational journal of molecular sciences2019

Current Trends in Applications of Circulatory Microchimerism Detection in Transplantation.

Hajnalka Andrikovics, Zoltán Őrfi, Nóra Meggyesi, András Bors, Lívia Varga, Petra Kövy, Zsófia Vilimszky, Fanni Kolics, László Gopcsa, Péter Reményi and 1 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Utility ofAnnals of laboratory medicine · 2025
    Article
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  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
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  12. Application of Blood Group Genotyping by Next-Generation Sequencing in Various Immunohaematology Cases.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2022
    Article
  13. Review
  14. Article
  15. A Dynamic Hanging-Drop System for Mesenchymal Stem Cell Culture.International journal of molecular sciences · 2020
    Article
  16. Cell-Free Nucleic Acids.International journal of molecular sciences · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hajnalka AndrikovicsLaboratory of Molecular Genetics, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
Zoltán ŐrfiLaboratory of Molecular Genetics, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
Nóra MeggyesiLaboratory of Molecular Genetics, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
András BorsLaboratory of Molecular Genetics, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
Lívia VargaSchool of PhD Studies, Semmelweis University, 1085 Budapest, Hungary.
Petra KövyLaboratory of Molecular Genetics, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
Zsófia VilimszkyLaboratory of Molecular Genetics, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
Fanni KolicsLaboratory of Molecular Genetics, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
László GopcsaDepartment of Hematology and Stem Cell Transplantation, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
Péter ReményiDepartment of Hematology and Stem Cell Transplantation, Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
Attila TordaiDepartment of Pathophysiology, Semmelweis University, 1089 Budapest, Hungary. tordai.attila@med.semmelweis-univ.hu.ORCID 0000-0001-6966-1622

Funding

Felsőoktatási Intézményi Kiválósági Pályázat FIKPF-SEJanos Bolyai Research Scholarship BO/00579/17/5Janos Bolyai Research Scholarship BO/00809/18/8National Research, Development and Innovation Office NVKP_16-1-2016-0005New National Excellence Program of the Ministry of Human Resources ÚNKP-18-4-SE-11
6 · The paper itself

Abstract

Primarily due to recent advances of detection techniques, microchimerism (the proportion of minor variant population is below 1%) has recently gained increasing attention in the field of transplantation. Availability of polymorphic markers, such as deletion insertion or single nucleotide polymorphisms along with a vast array of high sensitivity detection techniques, allow the accurate detection of small quantities of donor- or recipient-related materials. This diagnostic information can improve monitoring of allograft injuries in solid organ transplantations (SOT) as well as facilitate early detection of relapse in allogeneic hematopoietic stem cell transplantation (allo-HSCT). In the present review, genetic marker and detection platform options applicable for microchimerism detection are discussed. Furthermore, current results of relevant clinical studies in the context of microchimerism and SOT or allo-HSCT respectively are also summarized.

Indexed as

ChimerismDNAHematopoietic Stem Cell TransplantationHumansMicrosatellite RepeatsOrgan TransplantationPolymorphism, Single NucleotideTissue DonorsTransplantation ChimeraTransplantation, HomologousDNAdeletion/insertion polymorphismgenetic markerhematopoietic stem cell transplantationmicrochimerismsingle nucleotide polymorphismsolid organ transplantation

Identifiers

PMID31509957
PMCPMC6769866

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.