Evidence map›Paper›PMID 31509946›Full record

ArticleAnimals : an open access journal from MDPI2019

MicroRNA-152 Promotes Slow-Twitch Myofiber Formation via Targeting Uncoupling Protein-3 Gene.

Yong Zhang, Honglin Yan, Pan Zhou, Zhenzhen Zhang, Jingbo Liu, Hongfu Zhang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Article
  5. Article
  6. Effects of DietaryVeterinary sciences · 2025
    Article
  7. Review
  8. The Role of theAnimals : an open access journal from MDPI · 2024
    Article
  9. MiR-106a-5p by TargetingAnimals : an open access journal from MDPI · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yong ZhangSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China.
Honglin YanSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China.ORCID 0000-0002-2597-6902
Pan ZhouSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China.
Zhenzhen ZhangSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China.
Jingbo LiuSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China. liuswust@163.com.
Hongfu ZhangSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China.
Southwest University of Science and Technology · CN

Funding

the National Key Research and Development Program of China 2016YFD0500505the National Natural Science Foundation of China 31802069the Natural Science Foundation of Southwest University of Science and Technology 19zx7115
6 · The paper itself

Abstract

The differences of pork quality characteristics among different pig breeds mainly came from the differences in myofiber type compositions. Growing evidence indicated the key role of miRNAs in myofiber specification. In the present study, we found that miR-152 is more abundant in the slow-twitch myofiber-enriched muscles. However, its role in myofiber type transformation and myogenesis is largely unknown. Overexpression of miR-152 in porcine myotubes promoted the formation of slow-twitch myofibers and myogenesis. While, inhibition of miR-152 expression showed the opposite effect to miR-152 mimics transfection. The luciferase reporter analysis confirmed that miR-152 straightly targets the 3'-untranslated region (3'-UTR) of uncoupling protein 3 (

Indexed as

meat qualitymiR-152myofiber specificationmyogenesisporcine myoblastsUCP3

Identifiers

PMID31509946
PMCPMC6769457
OpenAlexW2972403094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.