ReviewStem cell reports2019
The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness.
Review in Stem cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- Organoids: a systematic review of ethical issues.Stem cell research & therapy · 2022Pooled it
- Transforming Brain Organoids Into Functional Platforms: Convergence of Engineering, Imaging, AI, and Ethics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ethical Challenges and Governance Strategies for Microphysiological Systems Technology.Biology · 2026Review
- Ethics and Regulation of Human Brain Organoid Research: Recommendations from the Asia Pacific Neuroethics Working Group.Asian bioethics review · 2026Article
- Manipulating embryogenesis and testing for potential: two real problems for the regulation of stem cell-based embryo models.Journal of medical ethics · 2026Article
- Ethical concerns about embodied brain organoids shaped by foundational distinctions and perceptions of consciousness.Scientific reports · 2026Article
- Ethical review key considerations for organoid applications in biomedical research-a systematic review.Frontiers in cell and developmental biology · 2026Review
- Views on the distribution of consciousness influence ethical judgements toward brain organoids as biological computers: an exploratory study.Neuroscience of consciousness · 2026Article
- Cerebral organoids and organoid intelligence: ethical challenges and governance pathway.Frontiers of medicine · 2025Article
- Human brain slice cultures: translational applications and ethical considerations.Life science alliance · 2025Review
- The ethical aspects of human organ-on-chip models: A mapping review.Stem cell reports · 2025Review
- Photoactivatable Cyclometalated Ir(III) Compound Penetrates the Blood-Brain Barrier in 3D Spheroidal and Advanced 3D Organoid Models of Inherently Resistant and Aggressive Brain Tumors.ACS pharmacology & translational science · 2025Article
- Moral Intuition Regarding the Possibility of Conscious Human Brain Organoids: An Experimental Ethics Study.Science and engineering ethics · 2024Article
- A tumorigenicity evaluation platform for cell therapies based on brain organoids.Translational neurodegeneration · 2024Article
- Promoting Alzheimer's disease research and therapy with stem cell technology.Stem cell research & therapy · 2024Review
- Organotypic culture of human brain explants as a preclinical model for AI-driven antiviral studies.EMBO molecular medicine · 2024Article
- Assembloid learning: opportunities and challenges for personalized approaches to brain functioning in health and disease.Frontiers in artificial intelligence · 2024Article
- The technology, opportunities, and challenges of Synthetic Biological Intelligence.Biotechnology advances · 2023Review
- Cerebral Organoid Research Ethics and Pinning the Tail on the Donkey.Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees · 2023Article
- Human Brain Organoids in Migraine Research: Pathogenesis and Drug Development.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, the use of three-dimensional neural tissues cultured in vitro and called "cerebral organoids" has advanced recapitulation of neural development and disease modeling studies. Along with such advances, cerebral organoid research, and associated concerns call for the elucidation of two points: (1) how cerebral organoid research is currently progressing and the future directions it is likely to take, especially in functional assessment of organoids, and (2) how we should solve ethical issues of possible consciousness in cerebral organoid research. This paper aims first to explore these two issues, and then to present implications and prospects for future cerebral organoid research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.