Evidence map›Paper›PMID 31509527›Full record

ArticlePLoS neglected tropical diseases2019

Development and validation of a pen side test for Rift Valley fever.

Catherine Cêtre-Sossah, Aurélie Pédarrieu, Mikael Juremalm, Petrus Jansen Van Vuren, Alejandro Brun, Ahmed Bezeid Ould El Mamy, Jean-Michel Héraud, Claudia Filippone, Jean-Pierre Ravalohery, Hassan Chaabihi and 4 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
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  13. "FastCheckViruses · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Catherine Cêtre-SossahASTRE, Univ Montpellier, CIRAD, INRA, Montpellier, France.ORCID 0000-0002-0869-1681
Aurélie PédarrieuASTRE, Univ Montpellier, CIRAD, INRA, Montpellier, France.
Mikael JuremalmBoehringer Ingelheim Svanova, Virdingsallé, Uppsala, Sweden.
Petrus Jansen Van VurenCentre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Diseases, Sandringham-Johannesburg, South Africa.ORCID 0000-0003-2862-7983
Alejandro BrunINIA-CISA, Valdeolmos, Madrid, Spain.
Ahmed Bezeid Ould El MamyONARDEL, service de pathologies infectieuses, Nouakchott, Mauritania.
Jean-Michel HéraudVirology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Claudia FilipponeVirology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Jean-Pierre RavaloheryVirology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Hassan ChaabihiAgate bioservices, Bagard, France.ORCID 0000-0002-8093-2179
Emmanuel AlbinaASTRE, Univ Montpellier, CIRAD, INRA, Montpellier, France.
Laure DommerguesCoopADEM - GDS Mayotte, Coconi, Mayotte, France.
Janusz PaweskaCentre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Diseases, Sandringham-Johannesburg, South Africa.
Eric CardinaleASTRE, Univ Montpellier, CIRAD, INRA, Montpellier, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRift Valley fever (RVF) is one of the main vector borne zoonotic diseases that affects a wide range of ruminants and human beings in Africa and the Arabian Peninsula. A rapid and specific test for RVF diagnosis at the site of a suspected outbreak is crucial for the implementation of control measures. METHODOLOGY/PRINCIPAL

findingsA first-line lateral flow immunochromatographic strip test (LFT) was developed for the detection of the nucleoprotein (N) of the RVF virus (RVFV). Its diagnostic performance characteristics were evaluated using reference stocks isolates recovered from different hosts and in geographic regions mimicking clinical specimens and from known RVF negative serum samples. A high level of diagnostic accuracy (DSe (35/35), DSp (167/169)) was observed, including the absence of cross-reactivity with viruses belonging to different genera. CONCLUSION/SIGNIFICANCE: The fact no specialized reagents and laboratory equipment are needed, make this assay a valuable, first-line diagnostic tool in resource-poor diagnostic territories for on-site RVFV detection, however the staff require training.

Indexed as

AnimalsArtiodactylaCulicidaeImmunoassayNucleoproteinsRift Valley FeverRift Valley fever virusSensitivity and SpecificityNucleoproteins

Identifiers

PMID31509527
PMCPMC6738586

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.