Evidence map›Paper›PMID 31509518›Full record

ArticleAging2019

Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan.

Julia Adelöf, Jaime M Ross, Stanley E Lazic, Madeleine Zetterberg, John Wiseman, Malin Hernebring

Abstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Model of Accelerated Aging in CB6F2 Mice Induced by Ionizing Radiation.Bulletin of experimental biology and medicine · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julia AdelöfDepartment of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg 41390, Sweden.
Jaime M RossDepartment of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA 02215, USA.
Stanley E LazicQuantitative Biology, Discovery Sciences, R&D AstraZeneca, Cambridge CB4 0WG, UK.
Madeleine ZetterbergDepartment of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg 41390, Sweden.
John WisemanDiscovery Biology, Discovery Sciences, R&D AstraZeneca, Gothenburg, Mölndal 43153, Sweden.
Malin HernebringDepartment of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg 41390, Sweden.

Funding

The role of epigenetics in age-related cognitive decline and Alzheimer’s diseaseK99AG055683 · NIA · HARVARD MEDICAL SCHOOL · PI ROSS, JAIME MARIE · 2017 to 2018
$248k
NIA NIH HHS K99 AG055683
6 · The paper itself

Abstract

Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies. The aim of this study is to determine age-related behavioral changes of F2 hybrid C57BL/6NxBALB/c male and female mice. Lifespan was followed (n

Indexed as

AdiposityAgingAnimalsExploratory BehaviorFemaleMaleMemoryMice, Inbred BALB CMice, Inbred C57BLSwimmingagingexploratory activityF2 hybrid micesex comparisonwater-based behavioral tests

Identifiers

PMID31509518
PMCPMC6756906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.