Evidence map›Paper›PMID 31509109›Full record

ArticleeLife2019

Calcium-driven regulation of voltage-sensing domains in BK channels.

Yenisleidy Lorenzo-Ceballos, Willy Carrasquel-Ursulaez, Karen Castillo, Osvaldo Alvarez, Ramon Latorre

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Tuning the gate and the gear: The LRRC26 (γ1) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channel.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Tuning the gate and the gear: The LRRC26 (bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. CaInternational journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Mechanism of voltage sensing in CaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Review
  12. Coupling of CaProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yenisleidy Lorenzo-CeballosDoctorado en Ciencias Mención Neurociencia, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.ORCID 0000-0003-4309-9314
Willy Carrasquel-UrsulaezCentro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.
Karen CastilloCentro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.
Osvaldo AlvarezCentro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.
Ramon LatorreCentro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.ORCID 0000-0002-6044-5795
University of Valparaíso · CLUniversity of Chile · CL

Funding

AFOSR No. FA9550-16-1-0384Chilean Ministry of Economy, Development, and Tourism Millennium Scientific Initiative P029-022-FCONICYT-PFCHA Doctoral fellowship No. 63140149FONDECYT Grant No. 1150273FONDECYT Grant No. 1180999FONDECYT Grant No. 1190203Millennium Scientific Initiative of the Chilean Ministry of Economy, Development, and Tourism P029-022-F
6 · The paper itself

Abstract

Allosteric interactions between the voltage-sensing domain (VSD), the Ca

Indexed as

CalciumCations, DivalentHumansLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsProtein BindingProtein DomainsCalciumCations, DivalentLarge-Conductance Calcium-Activated Potassium Channel alpha Subunitsallosteric couplingCa2+ bindingE. coligating currentsmolecular biophysicsstructural biologyxenopus

Identifiers

PMID31509109
PMCPMC6763263
OpenAlexW2972413715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.