Evidence map›Paper›PMID 31508794›Full record

ArticleJournal of applied oral science : revista FOB2019

Effect of avocado/soybean unsaponifiables on periodontal repair in rats with arthritis and induced periodontitis.

Jackeline do Nascimento Tsurumaki, Luiz Guilherme Freitas de Paula, Sabrina Garcia de Aquino, Elcio Marcantonio, Guilherme José Pimentel Lopes de Oliveira, Rosemary Adriana Chiérici Marcantonio

Open access · diamondAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied oral science : revista FOB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jackeline do Nascimento TsurumakiUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia de Araraquara, Departamento de Diagnóstico e Cirurgia, Araraquara, São Paulo, Brasil.
Luiz Guilherme Freitas de PaulaCentro Universitário de Anápolis, Faculdade de Odontologia (Unievangélica), Anápolis, Goiás, Brasil.
Sabrina Garcia de AquinoUniversidade Federal da Paraíba, Faculdade de Odontologia, Departamento de Ciências da Saúde, João Pessoa, Paraíba, Brasil.ORCID http://orcid.org/0000-0002-3988-1939
Elcio MarcantonioUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia de Araraquara, Departamento de Diagnóstico e Cirurgia, Araraquara, São Paulo, Brasil.ORCID http://orcid.org/0000-0003-1294-2305
Guilherme José Pimentel Lopes de OliveiraUniversidade Federal de Uberlândia, Faculdade de Odontologia, Departamento de Periodontia, Uberlândia, Minas Gerais, Brasil.ORCID http://orcid.org/0000-0001-8778-0115
Rosemary Adriana Chiérici MarcantonioUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia de Araraquara, Departamento de Diagnóstico e Cirurgia, Araraquara, São Paulo, Brasil.ORCID http://orcid.org/0000-0002-5052-7439
Universidade Estadual Paulista (Unesp) · BRUniversidade Evangelica de Goiás · BRUniversidade Federal da Paraíba · BRUniversidade Federal de Uberlândia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the effect of avocado/soybean unsaponifiables (ASU) on periodontal repair in rats with induced periodontitis and arthritis. METHODOLOGY: Forty-five rats were submitted to periodontitis induction by insertion of ligatures into the upper second molars, maintained for 15 days. These animals were randomly allocated to 3 groups according to the presence of induced arthritis (ART) and the application of the ASU: Control (CTR) group-healthy animals, where saline solution was administered; ART-animals with induced arthritis, where saline solution was administered; ART/ASU-animals with induced arthritis, where ASU (0.6 mg/ kg) was administered. The drugs were administered daily by gavage and the animals were euthanized after 7, 15 and 30 days of the ligature removal. Bone resorption, inflammatory infiltrate composition and marker proteins expression of the differentiation and formation of osteoclasts (RANKL and TRAP) were assessed.

resultsThe ART/ASU group presented higher bone volume than the ART group at 7 and 30 days after the ligature removal. Furthermore, the ART group presented higher quantity of inflammatory cells and expression of TRAP and RANKL than the other groups.

conclusionASU administration improves the repair of periodontal tissues in an experimental periodontitis model in rats with induced arthritis.

Indexed as

AnimalsArthritisGlycine maxImmunohistochemistryMalePeriodontitisPerseaPlant ExtractsRandom AllocationRANK LigandRatsReproducibility of ResultsTartrate-Resistant Acid PhosphataseTime FactorsTreatment OutcomeX-Ray MicrotomographyPlant ExtractsRANK LigandTartrate-Resistant Acid Phosphatase

Identifiers

PMID31508794
PMCPMC9648970
OpenAlexW2971961188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.