ArticleInternational journal of reproductive biomedicine2019
Effects of autologous platelet-rich plasma on endometrial expansion in patients undergoing frozen-thawed embryo transfer: A double-blind RCT.
Article in International journal of reproductive biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 7 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Efficacy of platelet-rich plasma or plasma rich in growth factors in the treatment of thin endometrium: a systematic review and meta-analysis of randomized controlled trials.Frontiers in endocrinology · 2026Pooled it
- The efficacy of adjuvant therapies in improving endometrial function of women undergoing assisted reproductive technology: a systematic review and network meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Network meta-analysis on the efficacy of different interventions for treating thin endometrium.Frontiers in endocrinology · 2025Pooled it
- Evolution of biotechnological advances and regenerative therapies for endometrial disorders: a systematic review.Human reproduction update · 2024Pooled it
- Efficacy of platelet-rich plasma in the treatment of thin endometrium: a meta-analysis of randomized controlled trials.BMC pregnancy and childbirth · 2024Pooled it
- Autologous platelet-rich plasma for assisted reproduction.The Cochrane database of systematic reviews · 2024Pooled it
- The efficacy of intrauterine infusion of platelet rich plasma in women undergoing assisted reproduction: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- Comparison of the efficacy of single vs. double autologous platelet-rich plasma intrauterine infusion on endometrial receptivity in thin endometrium patients: a prospective randomized controlled trial.Frontiers in endocrinology · 2025Trial
- Hysteroscopic injections of autologous endometrial cells and platelet-rich plasma in patients with thin endometrium: a pilot randomized study.Scientific reports · 2023Trial
- The Effects of Autologous Platelet-Rich Plasma on Pregnancy Outcomes in Repeated Implantation Failure Patients Undergoing Frozen Embryo Transfer: A Randomized Controlled Trial.Reproductive sciences (Thousand Oaks, Calif.) · 2022Trial
- Autologous platelet-rich plasma treatment for moderate-severe Asherman syndrome: the first experience.Journal of assisted reproduction and genetics · 2021Trial
- Intrauterine infusion and sub-endometrial injection of autologous platelet-rich plasma for thin endometrium: A systematic review and single-arm meta-analysis.Turkish journal of obstetrics and gynecology · 2026Article
- Effect of intrauterine administration of platelet-rich plasma two days before timed artificial insemination in dairy cows on endometrial thickness and conception rate.The Journal of veterinary medical science · 2026Article
- Efficacy and Safety of Fat Graft Myringoplasty Combined With Platelet-Rich Plasma for Managing Chronic Tympanic Membrane Perforations: A Systematic Review and Meta-Analysis.Clinical and experimental otorhinolaryngology · 2026Article
- Commentary: Regenerative therapies for refractory thin endometrium inFrontiers in cell and developmental biology · 2026Article
- Impact of Tamoxifen on Endometrial Thickness in Women With Thin Endometrium Following Estrogen Therapy During Frozen-Thawed Embryo Transfer.Clinical case reports · 2025Article
- Platelet-rich plasma therapy for thin endometrium: a comprehensive review.Archives of gynecology and obstetrics · 2025Review
- Genetic Associations ofInternational journal of molecular sciences · 2025Article
- Is it justified to offer intrauterine infusion of autologous PRP in women with repeated implantation failure?Human reproduction (Oxford, England) · 2025Review
- Study Protocol: Evaluating the Effect of Autologous Platelet-Rich Plasma Infusion in the Endometrial Cavity for Enhanced Embryo-Endometrium Synchrony in Patients with Repeated Implantation Failure.Journal of pharmacy & bioallied sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdequate endometrial growth is principal for implantation and pregnancy. Thin endometrium is associated with lower pregnancy rate in assisted reproductive technology. Some frozen-thawed embryo transfer cycles are cancelled due to inadequate endometrial growth.
objectiveTo assess the effectiveness of autologous platelet-rich plasma (PRP) intrauterine infusion for the treatment of thin endometrium. MATERIALS AND
methodsA total of 72 patients who had a history of cancelled frozen-thawed embryo transfer cycle due to the thin endometrium (
resultsEndometrial thickness increased at 48 hr after the first intervention in both groups. All participants needed second intervention due to an inadequate endometrial expansion. After second intervention, endometrial thickness was 7.21
conclusionAccording to this trial, PRP was effective in endometrial expansion in patients with refractory thin endometrium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.