ArticleJournal of orthopaedic translation2019
Discordance in diagnosis of osteoporosis by quantitative computed tomography and dual-energy X-ray absorptiometry in Chinese elderly men.
Article in Journal of orthopaedic translation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
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Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Deep Learning-Assisted Automated Diagnosis of Osteoporosis Based on Computed Tomography Scans: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- The diagnostic value of MRI-based vertebral bone quality score for osteoporosis or osteopenia in patients undergoing lumbar surgery: a meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Pooled it
- Changes in bone mineral density after bariatric surgery in patients of different ages or patients with different postoperative periods: a systematic review and meta-analysis.European journal of medical research · 2022Pooled it
- Osteoporosis: current diagnostic possibilities, a literature review.Przeglad menopauzalny = Menopause review · 2026Review
- Generalizable framework for multi-site bone density prediction using non-dominant wrist optical biomarkers.Biomedical optics express · 2026Article
- Quantitative CT-Derived Volumetric Bone Mineral Density Threshold for Predicting Cage Subsidence After Oblique Lumbar Interbody Fusion.Tomography (Ann Arbor, Mich.) · 2026Article
- Differences in lumbar spine bone mineral density measured by quantitative computed tomography and dual-energy X-ray absorptiometry: an age- and sex-specific analysis.Journal of orthopaedic surgery and research · 2026Article
- Correlation between the osteoporosis self-assessment tool for Asians index and QCT-derived bone parameters: a cross-sectional analysis of lumbar spine mineral density and content.Frontiers in surgery · 2026Article
- Article
- Association of triglyceride glucose index and volumetric bone mineral density in T2DM: fat distribution as a potential indirect link.Frontiers in cell and developmental biology · 2026Article
- Artificial intelligence in osteoporosis assessment using CT imaging: a scoping review.Frontiers in medicine · 2026Review
- Association between vertebral fracture risk and bone mineral density in patients with acromegaly.Pituitary · 2025Article
- Development of a LASSO dynamic prediction system for interbody cage subsidence following OLIF surgery.NPJ digital medicine · 2025Article
- Age- and sex-related changes in proximal humeral volumetric BMD assessed via chest CT with a deep learning-based segmentation model.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Enhanced diagnosis of osteoporosis using vision transformer with lumbar MRI.BMC medical imaging · 2025Article
- The diagnostic cutoff value of vertebral bone quality score for osteoporosis is significantly influenced by the magnetic field in patients undergoing lumbar surgery.Quantitative imaging in medicine and surgery · 2025Article
- Article
- Using Phantomless QCT for evaluating BMD evolution in maintenance hemodialysis patients.Scientific reports · 2025Article
- Criteria for osteoporosis diagnosis: a systematic review and meta-analysis of osteoporosis diagnostic studies with DXA and QCT.EClinicalMedicine · 2025Article
- The Relationship Between the Heterogeneity of Lumbar Vertebral Trabecular Bone Mineral Density Distribution and Osteoporotic Vertebral Fractures.Calcified tissue international · 2025Article
1 more citing papers are in PubMed but not listed here.
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7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of this study was to investigate the diagnostic discordance of osteoporosis by quantitative computed tomography (QCT) and dual-energy X-ray absorptiometry (DXA) in Chinese elderly men.
methodsA total of 313 males older than 60 years, who underwent both spinal QCT and lumbar spine and hip DXA in our department, were included. The diagnostic criteria established by the World Health Organisation in 1994 were used for DXA to diagnose osteoporosis, and the criteria recommended by the International Society of Clinical Densitometry were used for QCT. The osteoporosis detection rate by the two techniques was calculated, and the difference was compared. The minor discordance was considered present when the different diagnostic classes between the two techniques were adjacent. Major discordance was present when the diagnosis by one technique was osteoporosis and the other was normal. The computed tomography images were reviewed by radiologists to assess whether vertebral fracture, aorta calcification or degeneration was present.
resultsIn the 313 participants (mean age, 79.6 ± 7.2 years), the osteoporosis detection rate was 10.9% for DXA (lumbar spine and hip) and 45.1% for QCT, a significant difference (
conclusionOur study demonstrated that discordance was common when using QCT and DXA to diagnose osteoporosis and that spinal degeneration, aorta calcification and fracture obscure the bone mineral density measurement of spine by DXA. QCT is a more sensitive method of choice to identify osteoporosis in elderly Chinese men. THE TRANSLATIONAL POTENTIAL OF THIS ARTICLE: This study investigated the diagnostic discordance of osteoporosis by quantitative computed tomography (QCT) and dual-energy X-ray absorptiometry (DXA) in Chinese elderly men. The results demonstrated that QCT is a more sensitive method of choice to identify osteoporosis in elderly Chinese men. This work may help clinicians make an appropriate choice of technique for the accurate diagnosis of osteoporosis and identify the patients at high risk of osteoporosis who should be treated early to prevent fractures. This may influence the therapeutic plan and the overall prognosis of patients.
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