Evidence map›Paper›PMID 31508237›Full record

ArticleFertility research and practice2019

Number of motile spermatozoa inseminated and pregnancy outcomes in intrauterine insemination.

Palma G Gubert, Jessica Pudwell, Dean Van Vugt, Robert L Reid, Maria P Velez

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fertility research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000-2024).International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Review
  9. Observational
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Palma G GubertDepartment of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility, Queen's University, Kingston Health Sciences Centre, 76 Stuart Street, Victory 4, Kingston, ON K7L 2V7 Canada.
Jessica PudwellDepartment of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility, Queen's University, Kingston Health Sciences Centre, 76 Stuart Street, Victory 4, Kingston, ON K7L 2V7 Canada.
Dean Van VugtDepartment of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility, Queen's University, Kingston Health Sciences Centre, 76 Stuart Street, Victory 4, Kingston, ON K7L 2V7 Canada.
Robert L ReidDepartment of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility, Queen's University, Kingston Health Sciences Centre, 76 Stuart Street, Victory 4, Kingston, ON K7L 2V7 Canada.
Maria P VelezDepartment of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility, Queen's University, Kingston Health Sciences Centre, 76 Stuart Street, Victory 4, Kingston, ON K7L 2V7 Canada.ORCID 0000-0003-4834-8279
Queen's University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine whether age modifies the effect of the number of motile spermatozoa inseminated (NMSI) as a predictor of success in Intrauterine Insemination (IUI).

methodsThis retrospective cohort study included all patients who underwent IUI at an academic infertility center between October 2004 and June 2018. The primary outcome was clinical pregnancy (CP; a gestational sac and fetal heartbeat on ultrasound). Results were analyzed by patient factors including age, NMSI, duration of infertility, and cause of infertility, along with treatment factors such as number of follicles and ovulation induction protocol. Factors associated with the odds of achieving a clinical pregnancy were analyzed using binary logistic generalized estimating equations to control for clustering effects by couple. Female age was categorized as <35 years vs. ≥35 years.

resultsSeven hundred thirty-seven couples that underwent 2062 IUI cycles for heterogeneous indications were included. The overall CP rate was 15.1% per cycle, and the cumulative CP rate per couple was 35.9%. For females < 35 years, the odds of CP per cycle were reduced for NMSI categories (× 10

conclusionsThese results suggest that the NMSI can be used as a predictor of success in IUI in couples with women who are < 35 years of age; these patients should be counselled about their lower pregnancy rates when the NMSI is < 5.0 × 10

Indexed as

Assisted reproductionIntrauterine inseminationPregnancy rates

Identifiers

PMID31508237
PMCPMC6720098
OpenAlexW2972120417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.