ReviewF1000Research2019
Current outcomes and treatment of tetralogy of Fallot.
Review in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 1 synthesis or guideline pooled it, 167 citations in OpenAlex.
- Brazilian Guideline for Exercise Testing in Children and Adolescents - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- Trial
- Surgical repair of Tetralogy of Fallot - Long-term outcomes into the second decade after transannular patch repair and annulus-sparing patch repair.International journal of cardiology. Congenital heart disease · 2026Article
- NT-proBNP and hs-CRP may be useful biomarkers for identifying and stratifying repaired TOF patients at increased risk of RV systolic dysfunction.Journal of family medicine and primary care · 2026Article
- Early prone positioning after tetralogy of fallot repair in children: a retrospective cohort study of oxygenation, safety, and short-term outcomes.Frontiers in cardiovascular medicine · 2026Article
- Retrospective Analysis of Burden of Illness of Congenital Pulmonary Valve Disease in a Large, Commercially Insured US Population.Journal of health economics and outcomes research · 2026Article
- A Regional Approach to a Global Challenge: A Case Report of Caudal Anesthesia for Anoplasty in Tetralogy of Fallot With Pulmonary Atresia.Clinical case reports · 2026Article
- Patient-specific mixed reality for venus P-valve implantation: A novel approach to procedural planning.International journal of cardiology. Congenital heart disease · 2025Article
- Bleeding and Thrombotic Challenges in Children with uncorrected Cyanotic Congenital Heart Diseases (CCHD)- Experience from a tertiary care pediatric hospital.Pakistan journal of medical sciences · 2025Article
- The Hidden Regulators: MicroRNAs in Pediatric Heart Development and Disease.Journal of clinical medicine · 2025Review
- Revisiting Hepatic Fibrosis Risk in Congenital Heart Disease: Insights from Non-Invasive Markers and Echocardiography.Children (Basel, Switzerland) · 2025Article
- Management of pacemaker lead decubitus in an adult with repaired tetralogy of Fallot: A case report.International journal of surgery case reports · 2025Article
- Right ventricle remodelling: fromJournal of molecular and cellular cardiology plus · 2025Review
- Congenital Heart Defects in Patients with Anorectal Malformations: A Retrospective Cohort Study of 281 Patients.Pediatric cardiology · 2025Article
- Impact of smoking on cardiovascular health: Mechanisms, epidemiology and specific concerns regarding congenital heart disease.International journal of cardiology. Congenital heart disease · 2025Review
- Excellent medium to long term outcomes after cardiac surgery for moderate and complex congenital heart disease, regardless of geographic location.International journal of cardiology. Congenital heart disease · 2025Article
- Perioperative management and outcomes of surgical pulmonary valve replacement following tetralogy of fallot repair: A retrospective study.International journal of surgery case reports · 2025Article
- Quality of Life in Adults with Tetralogy of Fallot: Physical Limitations and Psychological Well-Being.Journal of cardiovascular development and disease · 2025Article
- Simple ECG-based score and clinical parameters to predict right ventricular dilation in patients with repaired tetralogy of fallot.Open heart · 2025Article
- Evolution of pulmonary artery reconstruction techniques: a focus on the neovalve from the right atrial appendage.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2025Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tetralogy of Fallot (ToF) is the most common type of cyanotic congenital heart disease. Since the first surgical repair in 1954, treatment has continuously improved. The treatment strategies currently used in the treatment of ToF result in excellent long-term survival (30 year survival ranges from 68.5% to 90.5%). However, residual problems such as right ventricular outflow tract obstruction, pulmonary regurgitation, and (ventricular) arrhythmia are common and often require re-interventions. Right ventricular dysfunction can be seen following longstanding pulmonary regurgitation and/or stenosis. Performing pulmonary valve replacement or relief of pulmonary stenosis before irreversible right ventricular dysfunction occurs is important, but determining the optimal timing of pulmonary valve replacement is challenging for several reasons. The biological mechanisms underlying dysfunction of the right ventricle as seen in longstanding pulmonary regurgitation are poorly understood. Different methods of assessing the right ventricle are used to predict impending dysfunction. The atrioventricular, ventriculo-arterial and interventricular interactions of the right ventricle play an important role in right ventricle performance, but are not fully elucidated. In this review we present a brief overview of the history of ToF, describe the treatment strategies currently used, and outline the long-term survival, residual lesions, and re-interventions following repair. We discuss important remaining challenges and present the current state of the art regarding these challenges.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.