ArticleActa endocrinologica (Bucharest, Romania : 2005)
FIRST DAY SERUM CALCIUM AND PARATHYROID HORMONE LEVELS AS PREDICTIVE FACTORS FOR SAFE DISCHARGE AFTER THYROIDECTOMY.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 8 citations in OpenAlex.
- Article
- Postoperative parathyroid hormone (PTH) is equivalent to perioperative PTH drop in predicting postsurgical hypoparathyroidism.Annals of the Royal College of Surgeons of England · 2024Article
- Role of postoperative intact serum PTH as an early predictor of severe post-thyroidectomy hypocalcemia: a prospective study.Journal of endocrinological investigation · 2021Article
- Development and validation of a new model for predicting hypocalcaemia after total thyroidectomy: the NuGra model.Langenbeck's archives of surgery · 2021Article
- PSEUDOPSEUDOHYPOPARATHYROIDISM AS A CAUSE OF FAHR SYNDROME: HYPOPARATHYROIDISM NOT THE ONLY ONE.Acta endocrinologica (Bucharest, Romania : 2005)Article
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8 authors at 1 institution in 1 country.
Funding
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Abstract
contextPermanent hypocalcemia is a rare but significant complication of thyroid surgery.
objectiveThe aim of this study was to identify predictive factors of hypocalcemia and hypoparathyroidism after thyroidectomy.
designStudy included 134 total patients submitted to thyroidectomy from two endocrine units (January 2015 - August 2016).
methodsWe measured total serum calcium (sCa) and intact PTH (iPTH) on postoperative day one and 1 month after surgery.
results118 patients were women with F/M ratio of 7.3/1 and a mean age of 51.8 years. 64 patients were included in group A (iPTH <12 pg/mL) and 70 patients in group B (iPTH >12 pg/mL). sCa and hypocalcemia symptoms were correlated with iPTH, measured 24 hours after surgery. The cut-off value was for sCa 8.05 mg/dL with a sensitivity of 85.29% and a specificity of 88.0% and for iPTH 11.2 pg/mL, with a sensitivity of 82.3% and a specificity of 71.0%. SCa (< 8.05 mg/dL) was a predictive factor with a 99 (IC95%:12.86-761.58) and iPTH (<11.2 pg/mL) with a 10.77 higher risk (CI95%: 3.83-30.30) to be associated with symptoms.
conclusionSCa and iPTH represent good predictive factors of early and safe hospital discharge and can predict the risk of prolonged and permanent hypoparathyroidism.
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