ReviewFrontiers in neurology2019
Spinal Cord Stimulation for Freezing of Gait: From Bench to Bedside.
Review in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Spinal Cord Stimulation for Gait Disorders in Parkinson's Disease.Journal of Parkinson's disease · 2023Pooled it
- Prevalence of freezing of gait in Parkinson's disease: a systematic review and meta-analysis.Journal of neurology · 2021Pooled it
- Efficacy of Repetitive Trans-spinal Magnetic Stimulation for Patients with Parkinson's Disease: a Randomised Controlled Trial.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Trial
- Feasibility of Real-Time Autonomous Functional Electrical Stimulation for Freezing of Gait.The European journal of neuroscience · 2026Article
- Advances in Brain Stimulation, Nanomedicine and the Use of Magnetoelectric Nanoparticles: Dopaminergic Alterations and Their Role in Neurodegeneration and Drug Addiction.Molecules (Basel, Switzerland) · 2024Review
- Fundamentals of deep brain stimulation for Parkinson's disease in clinical practice: part 2.Arquivos de neuro-psiquiatria · 2024Review
- Mesencephalic Locomotor Region and Presynaptic Inhibition during Anticipatory Postural Adjustments in People with Parkinson's Disease.Brain sciences · 2024Article
- A meta-analysis identifies factors predicting the future development of freezing of gait in Parkinson's disease.NPJ Parkinson's disease · 2023Review
- Temporal Investigations of the Changes in Presynaptic Inhibition Associated With Subthalamic Nucleus-Deep-Brain Stimulation.Journal of clinical neurology (Seoul, Korea) · 2023Article
- High cervical spinal cord stimulation in Parkinson's disease with dopamine-resistant axial disabilities: a case with 2-year follow-up.Journal of neurology · 2023Article
- Controversies and Clinical Applications of Non-Invasive Transspinal Magnetic Stimulation: A Critical Review and Exploratory Trial in Hereditary Spastic Paraplegia.Journal of clinical medicine · 2022Article
- Efficacy of caudal pedunculopontine nucleus stimulation on postural instability and gait disorders in Parkinson's disease.Acta neurochirurgica · 2022Article
- Case report: Combined therapy of bilateral subthalamic nucleus deep brain stimulation and spinal cord stimulation significantly improves motor function in a patient with multiple system atrophy with predominant parkinsonism.Frontiers in neuroscience · 2022Article
- Therapeutic Devices for Motor Symptoms in Parkinson's Disease: Current Progress and a Systematic Review of Recent Randomized Controlled Trials.Frontiers in aging neuroscience · 2022Review
- Algorithms for Automated Calibration of Transcutaneous Spinal Cord Stimulation to Facilitate Clinical Applications.Journal of clinical medicine · 2021Article
- Freezing of Gait in Parkinson's Disease: Invasive and Noninvasive Neuromodulation.Neuromodulation : journal of the International Neuromodulation Society · 2021Review
- Spinal cord stimulation therapy for gait dysfunction in progressive supranuclear palsy patients.Journal of neurology · 2021Article
- Future Therapeutic Strategies for Freezing of Gait in Parkinson's Disease.Frontiers in human neuroscience · 2021Review
- Current Perspectives on the Assessment and Management of Gait Disorders in Parkinson's Disease.Neuropsychiatric disease and treatment · 2021Review
- Deep Brain Stimulation Initiative: Toward Innovative Technology, New Disease Indications, and Approaches to Current and Future Clinical Challenges in Neuromodulation Therapy.Frontiers in neurology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spinal cord stimulation (SCS) has been used for the treatment of chronic pain for nearly five decades. With a high degree of efficacy and a low incidence of adverse events, it is now considered to be a suitable therapeutic alternative in most guidelines. Experimental studies suggest that SCS may also be used as a therapy for motor and gait dysfunction in parkinsonian states. The most common and disabling gait dysfunction in patients with Parkinson's disease (PD) is freezing of gait (FoG). We review the evolution of SCS for gait disorders from bench to bedside and discuss potential mechanisms of action, neural substrates, and clinical outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.