Evidence map›Paper›PMID 31507405›Full record

ArticleFrontiers in aging neuroscience2019

Brain Amide Proton Transfer Imaging of Rat With Alzheimer's Disease Using Saturation With Frequency Alternating RF Irradiation Method.

Runrun Wang, Peidong Chen, Zhiwei Shen, Guisen Lin, Gang Xiao, Zhuozhi Dai, Bingna Zhang, Yuanfeng Chen, Lihua Lai, Xiaodan Zong and 3 more

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Runrun WangDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Peidong ChenDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Zhiwei ShenDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Guisen LinDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Gang XiaoDepartment of Mathematics and Statistics, Hanshan Normal University, Chaozhou, China.
Zhuozhi DaiDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Bingna ZhangTranslational Medicine, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Yuanfeng ChenDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Lihua LaiDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Xiaodan ZongDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Yan LiDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Yanyan TangDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.
Renhua WuDepartment of Medical Imaging, The Second Affiliated Hospital, Shantou University Medical College, Shantou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloid-β (Aβ) deposits and some proteins play essential roles in the pathogenesis of Alzheimer's disease (AD). Amide proton transfer (APT) imaging, as an imaging modality to detect tissue protein, has shown promising features for the diagnosis of AD disease. In this study, we chose 10 AD model rats as the experimental group and 10 sham-operated rats as the control group. All the rats underwent a Y-maze test before APT image acquisition, using saturation with frequency alternating RF irradiation (APT

Indexed as

Alzheimer’s diseaseamide proton transferchemical exchange saturation transfermagnetic resonance imagingsaturation with alternating frequency RF irradiation

Identifiers

PMID31507405
PMCPMC6713910

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.