Evidence map›Paper›PMID 31507363›Full record

ArticleFrontiers in neuroscience2019

Protuberant Electrode Structures for Subretinal Electrical Stimulation: Modeling, Fabrication and

Pedro González Losada, Lionel Rousseau, Marjorie Grzeskowiak, Manon Valet, Diep Nguyen, Julie Dégardin, Elisabeth Dubus, Serge Picaud, Gaelle Lissorgues

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Cellular migration into a subretinal honeycomb-shaped prosthesis for high-resolution prosthetic vision.Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pedro González LosadaLaboratory ESYCOM, University Paris Est-ESIEE-MLV, Noisy-le-Grand, France.
Lionel RousseauLaboratory ESYCOM, University Paris Est-ESIEE-MLV, Noisy-le-Grand, France.
Marjorie GrzeskowiakLaboratory ESYCOM, University Paris Est-ESIEE-MLV, Noisy-le-Grand, France.
Manon ValetINSERM, CNRS, Institut de la Vision, Sorbonne Université, Paris, France.
Diep NguyenINSERM, CNRS, Institut de la Vision, Sorbonne Université, Paris, France.
Julie DégardinINSERM, CNRS, Institut de la Vision, Sorbonne Université, Paris, France.
Elisabeth DubusINSERM, CNRS, Institut de la Vision, Sorbonne Université, Paris, France.
Serge PicaudINSERM, CNRS, Institut de la Vision, Sorbonne Université, Paris, France.
Gaelle LissorguesLaboratory ESYCOM, University Paris Est-ESIEE-MLV, Noisy-le-Grand, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many neural interfaces used for therapeutic applications are based on extracellular electrical stimulation to control cell polarization and thus functional activity. Amongst them, retinal implants have been designed to restore visual perception in blind patients affected by photoreceptor degeneration diseases, such as age-related macular degeneration (AMD) or retinitis pigmentosa (RP). While designing such a neural interface, several aspects must be taken into account, like the stimulation efficiency related to the current distribution within the tissue, the bio-interface optimization to improve resolution and tissue integration, and the material biocompatibility associated with long-term aging. In this study, we investigate the use of original microelectrode geometries for subretinal stimulation. The proposed structures combine the use of 3D wells with protuberant mushroom shaped electrode structures in the bottom, implemented on a flexible substrate that allows the

Indexed as

3D microelectrodeelectrical stimulationFEMmicrofabricationretinal prosthesessubretinal

Identifiers

PMID31507363
PMCPMC6718636

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.