Evidence map›Paper›PMID 31507268›Full record

ArticleJournal of medical Internet research2019

Application of a Blockchain Platform to Manage and Secure Personal Genomic Data: A Case Study of LifeCODE.ai in China.

Xiao-Ling Jin, Miao Zhang, Zhongyun Zhou, Xiaoyu Yu

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Applications of Blockchain in the Medical Field: Narrative Review.Journal of medical Internet research · 2021
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
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  8. Article
  9. Is blockchain ready for orthopaedics? A systematic review.Journal of clinical orthopaedics and trauma · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiao-Ling JinManagement School, Shanghai University, Shanghai, China.ORCID 0000-0003-1277-2844
Miao ZhangManagement School, Shanghai University, Shanghai, China.ORCID 0000-0002-2086-9382
Zhongyun ZhouDepartment of Management Science and Engineering, School of Economics and Management, Tongji University, Shanghai, China.ORCID 0000-0003-4245-8733
Xiaoyu YuManagement School, Shanghai University, Shanghai, China.ORCID 0000-0003-0446-2010

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rapid development of genetic and genomic technologies, such as next-generation sequencing and genome editing, has made disease treatment much more precise and effective. The technologies' value can only be realized by the aggregation and analysis of people's genomic and health data. However, the collection and sharing of genomic data has many obstacles, including low data quality, information islands, tampering distortions, missing records, leaking of private data, and gray data transactions.

objectiveThis study aimed to prove that emerging blockchain technology provides a solution for the protection and management of sensitive personal genomic data because of its decentralization, traceability, encryption algorithms, and antitampering features.

methodsThis paper describes the case of a blockchain-based genomic big data platform, LifeCODE.ai, to illustrate the means by which blockchain enables the storage and management of genomic data from the perspectives of data ownership, data sharing, and data security.

resultsBlockchain opens up new avenues for dealing with data ownership, data sharing, and data security issues in genomic big data platforms and realizes the psychological empowerment of individuals in the platform.

conclusionsThe blockchain platform provides new possibilities for the management and security of genetic data and can help realize the psychological empowerment of individuals in the process, and consequently, the effects of data self-governance, incentive-sharing, and security improvement can be achieved. However, there are still some problems in the blockchain that have not been solved, and which require continuous in-depth research and innovation in the future.

Indexed as

BlockchainComputer SecurityInformation DisseminationAlgorithmsBig DataChinaGenomicsHumansMobile ApplicationsOwnershipPrivacySoftwareblockchaindata ownershipdata securitydata sharingdigital healthgenomics big data platform

Identifiers

PMID31507268
PMCPMC6786844

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.