Evidence map›Paper›PMID 31507261›Full record

ArticlePsychological medicine2020

Cognitive paths from trauma to posttraumatic stress disorder: a prospective study of Ehlers and Clark's model in survivors of assaults or road traffic collisions.

Esther T Beierl, Inga Böllinghaus, David M Clark, Edward Glucksman, Anke Ehlers

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Psychological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06669442 (The Effectiveness of Guided Imagery, a Mindfulness Technique, on PCL-5 Scores in Adult Women With Post-Traumatic Stress Disorder), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06669442 nacompletednot on this mapstarted 2025, after this paper: background citation

The Effectiveness of Guided Imagery, a Mindfulness Technique, on PCL-5 Scores in Adult Women With Post-Traumatic Stress Disorder

TypeinterventionalSponsorNova Southeastern UniversityRan2025 to 2025Enrolled15ConditionsPost Traumatic Stress Disorder PTSDArmsGuided Imagery
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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  6. Pre-trauma cognitive traits predict fear generalization and associated prefrontal functioning in a longitudinal rodent model.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Esther T BeierlUniversity of Oxford, Oxford, UK.ORCID 0000-0001-5358-6824
Inga BöllinghausKing's College London, London, UK.
David M ClarkUniversity of Oxford, Oxford, UK.
Edward GlucksmanKing's College Hospital NHS Foundation Trust, London, UK.
Anke EhlersUniversity of Oxford, Oxford, UK.ORCID 0000-0002-8742-0192
King's College London · GBKing's College Hospital NHS Foundation Trust · GBUniversity of Oxford · GB

Funding

Department of HealthWellcome Trust 069777/200796Wellcome Trust 200796/Z/16/Z
6 · The paper itself

Abstract

backgroundIndividual differences in cognitive responses to trauma may represent modifiable risk factors that could allow early identification, targeted early treatment and possibly prevention of chronic posttraumatic stress disorder (PTSD). Ehlers and Clark's cognitive model of PTSD suggests that negative appraisals, disjointed trauma memories, and unhelpful coping strategies maintain PTSD. These are thought to be influenced by cognitive processing during trauma. The aim of this study was to test this model prospectively with path analyses.

methodsParticipants (N = 828) were recruited from an emergency department following injury in a violent assault or road traffic collision and 700 participated in the 6-month assessments. Cognitive processing was assessed shortly after the event, negative appraisals, disjointed memories, and unhelpful coping strategies at 1 month, persistent PTSD symptom severity at 6 months, and early PTSD symptom severity at 2 weeks.

resultsCognitive variables, with trauma type and gender, explained 52% of the variance in PTSD symptom severity at 6 months. Including early symptom severity in the model did not explain more variance (53%). Early PTSD symptom severity, with trauma type and gender, only predicted 40%. Negative appraisals and disjointed memories predicted persistent symptom severity both directly and indirectly via unhelpful strategies. Peritraumatic processing predicted persistent symptom severity mainly indirectly. The effects of trauma type and gender were fully mediated by the cognitive factors.

conclusionsThe results are consistent with theoretically derived predictions and support cognitive factors as indicators of risk for chronic PTSD and as a target for the treatment and prevention of PTSD.

Indexed as

CognitionMemoryAccidents, TrafficAdultFemaleHumansMaleMiddle AgedProspective StudiesPsychiatric Status Rating ScalesSeverity of Illness IndexStress Disorders, Post-TraumaticViolenceYoung AdultAppraisalscognitive processingdissociationmemoryposttraumatic stress disorderrumination

Identifiers

PMID31507261
PMCPMC7557160
OpenAlexW2968477446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.