Evidence map›Paper›PMID 31506853›Full record

Trial reportJournal of clinical psychology in medical settings2020

Psychological Outcomes of a Cognitive Behavioral Therapy for Youth with Inflammatory Bowel Disease: Results of the HAPPY-IBD Randomized Controlled Trial at 6- and 12-Month Follow-Up.

Luuk Stapersma, Gertrude van den Brink, Jan van der Ende, Eva M Szigethy, Michael Groeneweg, Frederieke H de Bruijne, Manon H J Hillegers, Johanna C Escher, Elisabeth M W J Utens

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical psychology in medical settings, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02265588 (Reducing Symptoms of Depression and Anxiety in Adolescents With Inflammatory Bowel Disease in Order to Improve Quality of Life and the Clinical Course of Disease.), which is not on this map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02265588 nacompletednot on this map

Reducing Symptoms of Depression and Anxiety in Adolescents With Inflammatory Bowel Disease in Order to Improve Quality of Life and the Clinical Course of Disease.

TypeinterventionalSponsorErasmus Medical CenterRan2014 to 2017Enrolled70ConditionsInflammatory Bowel Disease (IBD), Ulcerative Colitis, Crohn's Disease, AnxietyArmsCognitive behavioral therapy
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Psychological interventions for treatment of inflammatory bowel disease.The Cochrane database of systematic reviews · 2025
    Pooled it
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  5. Article
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  7. Review
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  10. Introduction to the Special Issue: Advances in Psychogastroenterology.Journal of clinical psychology in medical settings · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Luuk StapersmaDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands.ORCID 0000-0001-8164-178X
Gertrude van den BrinkDepartment of Pediatric Gastroenterology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
Jan van der EndeDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands.
Eva M SzigethyDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Michael GroenewegDepartment of Pediatrics, Maasstad Hospital, Rotterdam, The Netherlands.
Frederieke H de BruijneDepartment of Gastroenterology, Maasstad Hospital, Rotterdam, The Netherlands.
Manon H J HillegersDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands.
Johanna C EscherDepartment of Pediatric Gastroenterology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
Elisabeth M W J UtensDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands. e.utens@erasmusmc.nl.
Erasmus MC - Sophia Children’s Hospital · NLMaasstad Ziekenhuis · NLAmsterdam UMC Location University of Amsterdam · NLUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Youth with inflammatory bowel disease (IBD) often experience psychological difficulties, such as anxiety and depression. This randomized controlled study tested whether a 3-month disease-specific cognitive behavioral therapy (CBT) in addition to standard medical care versus standard medical care only was effective in improving these youth's psychological outcomes. As this study was aimed at prevention, we included 70 youth (10-25 years) with IBD and symptoms of subclinical anxiety and/or depression, and measured psychological outcomes at 6- and 12-month follow-up. In general, participants in both groups showed improvements in anxiety, depression, health-related quality of life, social functioning, coping, and illness perceptions, sustained until 12 months follow-up. Overall, we found no differences between those receiving additional CBT and those receiving standard medical care only. We assume that this can be explained by the perceived low burden (both somatically and psychologically) or heightened awareness of psychological difficulties and IBD. ClinicalTrials.gov NCT02265588.

Indexed as

Adaptation, PsychologicalAdolescentAdultAnxietyAnxiety DisordersCognitive Behavioral TherapyDepressionFemaleFollow-Up StudiesHumansInflammatory Bowel DiseasesMaleQuality of LifeYoung AdultAdolescentsAnxietyCognitive behavioral therapyDepressionInflammatory bowel diseasePsychological outcomesYoung adults

Identifiers

PMID31506853
PMCPMC7462914
OpenAlexW2972619069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.