ArticleAMB Express2019
The significance of aspartate on NAD(H) biosynthesis and ABE fermentation in Clostridium acetobutylicum ATCC 824.
Article in AMB Express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 20 citations in OpenAlex.
- Concentration-dependent stimulatory and inhibitory effects of β-cyclocitral, longifolene, and β-ionone on Microcystis aeruginosa.World journal of microbiology & biotechnology · 2026Article
- A combination fermentation strategy for simultaneously increasing cellular NADP(H) level, biomass, and enzymatic activity of glufosinate dehydrogenase in Escherichia coli.Bioprocess and biosystems engineering · 2023Article
- Over-expressing NadA quinolinate synthase in Escherichia coli enhances the bioelectrochemistry in microbial fuel cells.Biology open · 2023Article
- NADH-based kinetic model for acetone-butanol-ethanol production byFrontiers in bioengineering and biotechnology · 2023Article
- Role of the GeneJournal of fungi (Basel, Switzerland) · 2022Article
- Construction of an Alternative NADAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Microbial upgrading of acetate into 2,3-butanediol and acetoin byBiotechnology for biofuels · 2020Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The co-factor NADH plays an important role in butanol biosynthesis. In this study, we found that aspartate could effectively improve the butanol production of Clostridium acetobutylicum ATCC 824. Further study showed that aspartate could be used as the precursor of NADH de novo synthesis in C. acetobutylicum ATCC 824. When 2 g/L aspartate was added, the transcription levels of essential genes (nadA, nadB and nadC) for NADH de novo synthesis were significantly higher than that of without aspartate addition. The levels of intracellular NAD
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