ArticleNature communications2019
Different brain networks mediate the effects of social and conditioned expectations on pain.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
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- Common and distinct neurofunctional signatures of dynamic naturalistic emotion regulation strategies.Nature communications · 2026Article
- Social information creates self-fulfilling prophecies in judgments of pain, vicarious pain, and cognitive effort.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- A neurofunctional signature of affective arousal generalizes across valence domains and distinguishes subjective experience from autonomic reactivity.Nature communications · 2025Article
- Expectation generation and its effect on subsequent pain and visual perception.PLoS computational biology · 2025Article
- Spatiotemporal integration of contextual and sensory information within the cortical hierarchy in human pain experience.PLoS biology · 2024Article
- A structural MRI marker predicts individual differences in impulsivity and classifies patients with behavioral-variant frontotemporal dementia from matched controls.bioRxiv : the preprint server for biology · 2024Article
- A computational mechanism of cue-stimulus integration for pain in the brain.Science advances · 2024Article
- Placebo treatment affects brain systems related to affective and cognitive processes, but not nociceptive pain.Nature communications · 2024Article
- Interpersonal physiological and psychological synchrony predict the social transmission of nocebo hyperalgesia between individuals.Communications psychology · 2024Article
- The social transmission of empathy relies on observational reinforcement learning.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The central renin-angiotensin system: A genetic pathway, functional decoding, and selective target engagement characterization in humans.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Brain mediators of biased social learning of self-perception in social anxiety disorder.Translational psychiatry · 2023Article
- Implicit, But Not Explicit, Emotion Regulation Relieves Unpleasant Neural Responses Evoked by High-Intensity Negative Images.Neuroscience bulletin · 2023Article
- Peer-to-peer: The Social Transmission of Symptoms Online.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Article
- Targeting neural correlates of placebo effects.Cognitive, affective & behavioral neuroscience · 2023Review
- An fMRI-Based Brain Marker of Individual Differences in Delay Discounting.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Article
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Authors and funding
4 authors.
Funding
Abstract
Information about others' experiences can strongly influence our own feelings and decisions. But how does such social information affect the neural generation of affective experience, and are the brain mechanisms involved distinct from those that mediate other types of expectation effects? Here, we used fMRI to dissociate the brain mediators of social influence and associative learning effects on pain. Participants viewed symbolic depictions of other participants' pain ratings (social information) and classically conditioned pain-predictive cues before experiencing painful heat. Social information and conditioned stimuli each had significant effects on pain ratings, and both effects were mediated by self-reported expectations. Yet, these effects were mediated by largely separable brain activity patterns, involving different large-scale functional networks. These results show that learned versus socially instructed expectations modulate pain via partially different mechanisms-a distinction that should be accounted for by theories of predictive coding and related top-down influences.
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