Evidence map›Paper›PMID 31506295›Full record

ArticleThe Journal of biological chemistry2019

c-di-AMP assists osmoadaptation by regulating the

Johannes Gibhardt, Gregor Hoffmann, Asan Turdiev, Mengyi Wang, Vincent T Lee, Fabian M Commichau

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
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  3. TrkA ofMicrobiology (Reading, England) · 2025
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  8. Bacterial cell volume regulation and the importance of cyclic di-AMP.Microbiology and molecular biology reviews : MMBR · 2024
    Review
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  11. Article
  12. Article
  13. Cyclic di-AMP traps proton-coupled KNature communications · 2023
    Article
  14. Article
  15. Review
  16. C-di-AMP Is a Second Messenger inMicroorganisms · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Johannes GibhardtDepartment of General Microbiology, Institute for Microbiology and Genetics, Georg-August University Göttingen, D-37077 Göttingen, Germany.ORCID 0000-0001-9322-0018
Gregor HoffmannDepartment of General Microbiology, Institute for Microbiology and Genetics, Georg-August University Göttingen, D-37077 Göttingen, Germany.
Asan TurdievDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742.
Mengyi WangDepartment of General Microbiology, Institute for Microbiology and Genetics, Georg-August University Göttingen, D-37077 Göttingen, Germany.
Vincent T LeeDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742.
Fabian M CommichauDepartment of General Microbiology, Institute for Microbiology and Genetics, Georg-August University Göttingen, D-37077 Göttingen, Germany fcommic1@gwdg.de.ORCID 0000-0003-0323-7479
University of Göttingen · DEUniversity of Maryland, College Park · US

Funding

Training in Host-pathogens interactionsT32AI089621 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI LEE, VINCENT T, MCIVER, KEVIN S. · 2010 to 2025
$2.1M
NIAID NIH HHS T32 AI089621
6 · The paper itself

Abstract

Many bacteria and some archaea produce the second messenger cyclic diadenosine monophosphate (c-di-AMP). c-di-AMP controls the uptake of osmolytes in Firmicutes, including the human pathogen

Indexed as

Osmotic PressureBacterial ProteinsDinucleoside PhosphatesListeria monocytogenesMembrane Transport ProteinsPotassiumProtein DomainsSequence Homology, Amino AcidBacterial Proteinscyclic diadenosine phosphateDinucleoside PhosphatesMembrane Transport ProteinsPotassiumcyclic diadenosine monophosphate (c-di-AMP)Escherichia coli (E. coli)Gram-positive bacteriaion transportosmoadaptationosmoregulationosmotic swellingregulationsecond messengersignal transductiontransporterturgor

Identifiers

PMID31506295
PMCPMC6827311
OpenAlexW2972929810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.