Evidence map›Paper›PMID 31506105›Full record

ArticleBMC research notes2019

Clonal diversity of Haemophilus influenzae carriage isolated from under the age of 6 years children.

Fahimeh Shooraj, Bahman Mirzaei, Seyed Fazlollah Mousavi, Farzaneh Hosseini

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In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Epidemiology ofAccess microbiology · 2023
    Article
  3. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fahimeh ShoorajDepartment of Microbiology, Pasteur Institute of Iran, Tehran, Iran.
Bahman MirzaeiDepartment of Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Seyed Fazlollah MousaviDepartment of Microbiology, Pasteur Institute of Iran, Tehran, Iran. mousavi@pasteur.ac.ir.
Farzaneh HosseiniDepartment of Microbiology, Faculty of Biology, Islamic Azad University, North Branch, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPharyngeal carriers such as H. influenzae seem to constitute the only reservoir and probably the only transmission vehicle of the invasive disease. The aims of this study were to estimate the prevalence of H. influenzae carriage, to characterize antibiotic susceptibility, and to explore genetic diversity of H. influenzae isolates. Sampling was carried out as nasopharynx swabs among children less than 6 years old volunteers. After traditional biochemical tests, isolates were confirmed by targeting omp6 sequence. Following the susceptibility tests, genomic diversity of strains was analyzed by Pulsed-Field Gel Electrophoresis procedure.

resultsOut of 328 nasopharynx swabs, 73 strains were identified as H. influenzae. Among H. influenzae isolates, resistance to chloramphenicol (42%) and ampicillin (43%) was observed. Levofloxacin is the most effective antibiotic and the least effect belonged to tetracycline. By genomic analysis of selected H. influenza, 28 PFGE patterns were achieved among which 11 patterns included at least 2 strains. All strains clustered into 25 different clones. The dendrogram analysis of the isolated H. influenzae strains showed that some of these strains had a clonal relationship and common genetic origin. According to our results, antibiotic resistance didn't show any significant correlation with the clonality of strains.

Indexed as

Genetic VariationAnti-Bacterial AgentsCarrier StateChild, PreschoolCluster AnalysisElectrophoresis, Gel, Pulsed-FieldFemaleHaemophilus InfectionsHaemophilus influenzaeHumansIranMaleMicrobial Sensitivity TestsNasopharynxSpecies SpecificityAnti-Bacterial AgentsAntimicrobial resistanceGenomic analysisHemophilus influenzaePFGE

Identifiers

PMID31506105
PMCPMC6737650

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