Evidence map›Paper›PMID 31506082›Full record

ArticleBMC complementary and alternative medicine2019

A biological extract of turmeric (Curcuma longa) modulates response of cartilage explants to lipopolysaccharide.

Wendy Pearson, Laima S Kott

Abstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wendy PearsonDepartment of Animal Biosciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. wpearson@uoguelph.ca.ORCID http://orcid.org/0000-0002-3635-4594
Laima S KottDepartment of Plant Agriculture, University of Guelph, Guelph, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTurmeric is commonly used as a dietary treatment for inflammation, but few studies have evaluated the direct effect of turmeric on cartilage. The purpose of this study was to characterize cartilage explants' inflammatory responses to lipopolysaccharide in the presence of a simulated biological extract of turmeric.

methodsTurmeric was incubated in simulated gastric and intestinal fluid, followed by inclusion of liver microsomes and NADPH. The resulting extract (TUR

resultsTUR

conclusionsThese data contribute to the growing body of evidence for the utility of turmeric as an intervention for cartilage inflammation.

Indexed as

AnimalsAnti-Inflammatory AgentsCartilageCurcumaDinoprostoneGlycosaminoglycansIn Vitro TechniquesLipopolysaccharidesMaleNitric OxidePlant ExtractsRatsSwineAnti-Inflammatory AgentsDinoprostoneGlycosaminoglycansLipopolysaccharidesNitric OxidePlant Extractsturmeric extractArthritisCartilage inflammationHepatic metabolismSimulated digestionTurmeric

Identifiers

PMID31506082
PMCPMC6737590

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.