Evidence map›Paper›PMID 31506034›Full record

ArticleBiology letters2019

Retention of fish-like odontode overgrowth in Permian tetrapod dentition supports outside-in theory of tooth origins.

Yara Haridy, Bryan M Gee, Florian Witzmann, Joseph J Bevitt, Robert R Reisz

Open access · bronzeAbstract read
In one paragraph

Article in Biology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Teeth outside the jaw: Evolution and development of the toothed head clasper in chimaeras.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. The conundrum of pharyngeal teeth origin: the role of germ layers, pouches, and gill slits.Biological reviews of the Cambridge Philosophical Society · 2022
    Review
  6. Article
  7. Multiple epithelia are required to develop teeth deep inside the pharynx.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Yara HaridyDepartment of Biology, University of Toronto Mississauga, Ontario, Canada.
Bryan M GeeDepartment of Biology, University of Toronto Mississauga, Ontario, Canada.
Florian WitzmannMuseum für Naturkunde, Leibniz-Institut für Evolutions- und Biodiversitätsforschung, Berlin, Germany.
Joseph J BevittAustralian Centre for Neutron Scattering, Australian Nuclear Science and Technology Organisation, New South Wales, Australia.
Robert R ReiszInternational Center of Future Science, Dinosaur Evolution Research Centre, Jilin University, Changchun, People's Republic of China.
Museum für Naturkunde · DEAustralian Nuclear Science and Technology Organisation · AUJilin University · CNUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Teeth are often thought of as structures that line the margins of the mouth; however, tooth-like structures called odontodes are commonly found on the dermal bones of many Palaeozoic vertebrates including early jawless fishes. 'Odontode' is a generalized term for all tooth-like dentine structures that have homologous tissues and development. This definition includes true teeth and the odontodes of early 'fishes', which have been recently examined to gain new insights into the still unresolved origin of teeth. Two leading hypotheses are frequently referenced in this debate: the 'outside-in' hypothesis, which posits that dermal odontodes evolutionarily migrate into the oral cavity, and the 'inside-out' hypothesis, which posits that teeth originated in the oropharyngeal cavity and then moved outwards into the oral cavity. Here, we show that, unlike the well-known one-to-one replacement patterns of marginal dentition, the palatal dentition of the early Permian tetrapods, including the dissorophoid amphibian

Indexed as

DentitionToothAnimalsBiological EvolutionJawVertebratesdental evolutiondentitionodontodeovergrowthtooth origins

Identifiers

PMID31506034
PMCPMC6769137
OpenAlexW2972571418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.