Evidence map›Paper›PMID 31505940›Full record

ArticleCirculation. Heart failure2019

Prevalence of American Heart Association Heart Failure Stages in Black and White Young and Middle-Aged Adults: The CARDIA Study.

Samuel S Gidding, Donald Lloyd-Jones, Joao Lima, Bharat Ambale-Venkatesh, Sanjiv J Shah, Ravi Shah, Cora E Lewis, David R Jacobs, Norrina B Allen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Heart failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
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  10. Preventing new-onset heart failure: Intervening at stage A.American journal of preventive cardiology · 2023
    Review
  11. Article
  12. Article
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  18. Age-Related Development of Cardiac Remodeling and Dysfunction in Young Black and White Adults: The Coronary Artery Risk Development in Young Adults Study.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Samuel S GiddingNemours Cardiac Center, A.I. DuPont Hospital for Children, Wilmington, DE (S.S.G.).
Donald Lloyd-JonesDepartment of Preventive Medicine (D.L.-J., N.B.A.), Feinberg Medical School, Northwestern University, Chicago, IL.
Joao LimaDepartment of Internal Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD (J.L., B.A.-V.).
Bharat Ambale-VenkateshDepartment of Internal Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD (J.L., B.A.-V.).
Sanjiv J ShahDepartment of Internal Medicine (S.J.S.), Feinberg Medical School, Northwestern University, Chicago, IL.
Ravi ShahDivision of Cardiology, Massachusetts General Hospital, Boston (R.S.).
Cora E LewisDivision of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham (C.E.L.).
David R JacobsSchool of Public Health University of Minnesota, Minneapolis (D.R.J.).
Norrina B AllenDepartment of Preventive Medicine (D.L.-J., N.B.A.), Feinberg Medical School, Northwestern University, Chicago, IL.

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI W Timothy GARVEY · 2013 to 2026
$19.5M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095168 · HC · JOHNS HOPKINS UNIVERSITY · PI BLUEMKE, DAVID A. · 1999 to 2000
$375k
NHLBI NIH HHS HHSN268201800003INHLBI NIH HHS HHSN268201800004INHLBI NIH HHS HHSN268201800005INHLBI NIH HHS HHSN268201800006INHLBI NIH HHS HHSN268201800007INHLBI NIH HHS N01 HC095168NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

backgroundStaging criteria for heart failure (HF) range from stage 0 (without risk) to being at risk (stage A) to presence of cardiac structural/functional abnormalities (stage B) to symptomatic/end stage (stages C/D). There are limited data on the prevalence of these stages in early adulthood and predictors of HF stage and symptoms in middle age. METHODS AND

resultsThe CARDIA study (Coronary Artery Risk Development in Young Adults)-a cohort of generally healthy black and white men and women-collected phenotypic, echocardiographic, and outcomes data at the year 5 and year 30 examinations when participants were 22 to 37 and 47 to 62 years of age. Prevalence of HF stages was calculated and relationship of year 5 stage to year 30 classification and outcomes was assessed. At year 5, 2189 participants had complete data. Prevalence of HF stage A/B increased from 24% to 76% in black men, from 13% to 64% in white men, from 34% to 81% in black women, and from 13% to 56% in white women. Blacks were more likely to be in any stage or with morbidity at both time points because of higher risk factor prevalence. Of 33 participants with HF or HF deaths by year 30, 21 (64%) had been in stage A or B at year 5. Only 6 participants at year 5 in stage A (at risk) improved risk status at year 30.

conclusionsRisk for HF increased in participants from 1990 (age 22-37 years) to 2015 (age 47-62 years). Symptomatic HF or death from HF is associated with HF stage at 22 to 37 years of age. Blacks are disproportionately affected.

Indexed as

Black or African AmericanWhite PeopleAdultCoronary Artery DiseaseDisease ProgressionFemaleHeart FailureHumansLongitudinal StudiesMaleMiddle AgedPractice Guidelines as TopicPrevalenceUnited StatesYoung Adultcohort studiesechocardiographyheart failureUnited States

Identifiers

PMID31505940
PMCPMC6741433

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.