Evidence map›Paper›PMID 31505835›Full record

ArticleMarine drugs2019

Identification and Characterization of a Novel Protein ASP-3 Purified from

Zhongyi Guo, Hui Shi, Chunlei Li, Yuanyuan Luo, Sixue Bi, Rongmin Yu, Haoran Wang, Wanying Liu, Jianhua Zhu, Weijuan Huang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Investigation of Anticancer Peptides Derived fromMolecules (Basel, Switzerland) · 2025
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  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Zhongyi GuoDepartment of Pharmacology, College of Pharmacy, Jinan University, Guangzhou 510632, China. joey444@163.com.
Hui ShiBiotechnological Institute of Chinese Materia Medica, Jinan University, Guangzhou 510632, China. sh613050@163.com.
Chunlei LiBiotechnological Institute of Chinese Materia Medica, Jinan University, Guangzhou 510632, China. lcl992@126.com.
Yuanyuan LuoBiotechnological Institute of Chinese Materia Medica, Jinan University, Guangzhou 510632, China. yyluooo@163.com.
Sixue BiDepartment of Pharmacology, College of Pharmacy, Jinan University, Guangzhou 510632, China. shuimuliunian@163.com.
Rongmin YuBiotechnological Institute of Chinese Materia Medica, Jinan University, Guangzhou 510632, China. tyrm@jnu.edu.cn.
Haoran WangBroad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02142, USA. Haoran.wang@neolandbio.com.
Wanying LiuBiotechnological Institute of Chinese Materia Medica, Jinan University, Guangzhou 510632, China. lwy5464@stu2017.jnu.edu.cn.
Jianhua ZhuBiotechnological Institute of Chinese Materia Medica, Jinan University, Guangzhou 510632, China. tzhujh@jnu.edu.cn.
Weijuan HuangDepartment of Pharmacology, College of Pharmacy, Jinan University, Guangzhou 510632, China. huangjuan415@163.com.
Liyan SongDepartment of Pharmacology, College of Pharmacy, Jinan University, Guangzhou 510632, China. tsly@jnu.edu.cn.
Jinan University · CNBroad Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diverse bioactive substances derived from marine organisms have been attracting growing attention. Besides small molecules and polypeptides, numerous studies have shown that marine proteins also exhibit antitumor activities. Small anticancer proteins can be expressed in vivo by viral vectors to exert local and long-term anticancer effects. Herein, we purified and characterized a novel protein (ASP-3) with unique antitumor activity from

Indexed as

Angiogenesis InhibitorsAnimalsAnimals, Genetically ModifiedAntineoplastic AgentsArcidaeBiological ProductsCarcinoma, HepatocellularCell LineCell Line, TumorCell ProliferationFemaleHep G2 CellsHumansHuman Umbilical Vein Endothelial CellsLiver NeoplasmsMaleAngiogenesis InhibitorsAntineoplastic AgentsBiological ProductsProteinsVascular Endothelial Growth Factor Receptor-2antitumor mechanismArca subcrenata proteinstructural characterization

Identifiers

PMID31505835
PMCPMC6780846
OpenAlexW2972480285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.