ReviewInternational journal of molecular sciences2019
In Search for the Membrane Regulators of Archaea.
Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- A New Era for Using Natural Pigments: The Case of the CBiotechnology and applied biochemistry · 2026Review
- Marine Cold Seep ANME-2/SRB Consortia Produce Their Lipid Biomass From Inorganic Carbon.Environmental microbiology · 2025Article
- Unusual Genomic and Biochemical Features ofInternational journal of molecular sciences · 2024Article
- Microbial Bacterioruberin: A Comprehensive Review.Indian journal of microbiology · 2024Review
- The biosynthesis mechanism of bacterioruberin in halophilic archaea revealed by genome and transcriptome analysis.Applied and environmental microbiology · 2024Article
- Nitrogen and sulfur for phosphorus: Lipidome adaptation of anaerobic sulfate-reducing bacteria in phosphorus-deprived conditions.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Unraveling the multiplicity of geranylgeranyl reductases in Archaea: potential roles in saturation of terpenoids.Extremophiles : life under extreme conditions · 2024Review
- Pilot Lipidomics Study of Copepods: Investigation of Potential Lipid-Based Biomarkers for the Early Detection and Quantification of the Biological Effects of Climate Change on the Oceanic Food Chain.Life (Basel, Switzerland) · 2023Article
- Lipid environment modulates processivity and kinetics of a presenilin homolog acting on multiple substrates in vitro.The Journal of biological chemistry · 2023Article
- Membrane Adaptations and Cellular Responses ofInternational journal of molecular sciences · 2023Article
- Integration of Untargeted Metabolomics and Microbial Community Analyses to Characterize Distinct Deep-Sea Methane Seeps.Frontiers in Marine Science · 2023Article
- Membrane lipid and expression responses ofFrontiers in microbiology · 2023Article
- Vesicular and Planar Membranes of Archaea Lipids: Unusual Physical Properties and Biomedical Applications.International journal of molecular sciences · 2022Review
- Lipid biomarkers: molecular tools for illuminating the history of microbial life.Nature reviews. Microbiology · 2022Review
- The Exploration of theFrontiers in microbiology · 2022Article
- Lovastatin as a supplement to mitigate rumen methanogenesis: an overview.Journal of animal science and biotechnology · 2021Review
- Non-Polar Lipids as Regulators of Membrane Properties in Archaeal Lipid Bilayer Mimics.International journal of molecular sciences · 2021Article
- Characterisation of a synthetic Archeal membrane reveals a possible new adaptation route to extreme conditions.Communications biology · 2021Article
- Supercritical-COScientific reports · 2021Article
- Phytosterol Profiles, Genomes and Enzymes - An Overview.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Membrane regulators such as sterols and hopanoids play a major role in the physiological and physicochemical adaptation of the different plasmic membranes in Eukarya and Bacteria. They are key to the functionalization and the spatialization of the membrane, and therefore indispensable for the cell cycle. No archaeon has been found to be able to synthesize sterols or hopanoids to date. They also lack homologs of the genes responsible for the synthesis of these membrane regulators. Due to their divergent membrane lipid composition, the question whether archaea require membrane regulators, and if so, what is their nature, remains open. In this review, we review evidence for the existence of membrane regulators in Archaea, and propose tentative location and biological functions. It is likely that no membrane regulator is shared by all archaea, but that they may use different polyterpenes, such as carotenoids, polyprenols, quinones and apolar polyisoprenoids, in response to specific stressors or physiological needs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.