Evidence map›Paper›PMID 31505752›Full record

ReviewMolecules (Basel, Switzerland)2019

Perspective on the Therapeutics of Anti-Snake Venom.

Isabel Gómez-Betancur, Vedanjali Gogineni, Andrea Salazar-Ospina, Francisco León

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Comparative Hemostatic Effects ofBiochemistry research international · 2026
    Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Contemporary Insights into the Biological Mechanisms ofInternational journal of environmental research and public health · 2024
    Review
  11. Review
  12. Unraveling snake venom phospholipase APharmacological reports : PR · 2023
    Review
  13. Review
  14. Glutamine amelioratesThe journal of venomous animals and toxins including tropical diseases · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Isabel Gómez-BetancurOphidism-Scorpionism Program, Faculty of Pharmaceutical and Food Sciences, University of Antioquia UdeA, Medellín 1226, Colombia. isabel.gomez@inemjose.edu.co.ORCID 0000-0003-2550-892X
Vedanjali GogineniAnalytical Department, Cambrex Pharmaceuticals, Charles City, IA 50616, USA. vedanjalig@gmail.com.ORCID 0000-0002-2506-7434
Andrea Salazar-OspinaResearch group in Pharmacy Regency Technology, Faculty of Pharmaceutical and Food Sciences University of Antioquia UdeA, Medellín 1226, Colombia. andrea.salazaro@udea.edu.co.
Francisco LeónCollege of Pharmacy, University of Florida, Gainesville, FL 32610, USA. jleonoyola@cop.ufl.edu.ORCID 0000-0002-5064-2381
Universidad de Antioquia · COUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Snakebite envenomation is a life-threatening disease that was recently re-included as a neglected tropical disease (NTD), affecting millions of people in tropical and subtropical areas of the world. Improvement in the therapeutic approaches to envenomation is required to palliate the morbidity and mortality effects of this NTD. The specific therapeutic treatment for this NTD uses snake antivenom immunoglobulins. Unfortunately, access to these vital drugs is limited, principally due to their cost. Different ethnic groups in the affected regions have achieved notable success in treatment for centuries using natural sources, especially plants, to mitigate the effects of snake envenomation. The ethnopharmacological approach is essential to identify the potential metabolites or derivatives needed to treat this important NTD. Here, the authors describe specific therapeutic snakebite envenomation treatments and conduct a review on different strategies to identify the potential agents that can mitigate the effects of the venoms. The study also covers an increased number of literature reports on the ability of natural sources, particularly plants, to treat snakebites, along with their mechanisms, drawbacks and future perspectives.

Indexed as

AnimalsAntiveninsEthnopharmacologyHumansSnake BitesSnakesSnake VenomsAntiveninsSnake VenomsAnti-venommedicinal plantsplant constituentssnakebite treatmentsnake venom

Identifiers

PMID31505752
PMCPMC6767026
OpenAlexW2972298886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.