ArticleThe Journal of nutrition2018
Dietary Supplement Ingredient Database (DSID) and the Application of Analytically Based Estimates of Ingredient Amount to Intake Calculations.
Article in The Journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Trial
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- Strengthening Dietary Supplement Research: An Expanded Priority for the NIH Office of Dietary Supplements.The American journal of clinical nutrition · 2025Article
- Testing the amount of nicotinamide mononucleotide and urolithin A as compared to the label claim.GeroScience · 2024Article
- The Evolution of Science and Regulation of Dietary Supplements: Past, Present, and Future.The Journal of nutrition · 2024Review
- Hemp-Derived CBD Used in Food and Food Supplements.Molecules (Basel, Switzerland) · 2023Review
- Hidden sodium in effervescent-tablet dietary supplements and over-the-counter drugs: a comparative cross-sectional study.BMJ open · 2023Article
- Iodine in Foods and Dietary Supplements: A Collaborative Database Developed by NIH, FDA and USDA.Journal of food composition and analysis : an official publication of the United Nations University, International Network of Food Data Systems · 2022Article
- Efficacy of various prescribed vitamin D supplementation regimens on 25-hydroxyvitamin D serum levels in long-term care.Public health nutrition · 2022Article
- The Importance of Reference Materials and Method Validation for Advancing Research on the Health Effects of Dietary Supplements and Other Natural Products.Frontiers in nutrition · 2021Review
- A Review of Hemp as Food and Nutritional Supplement.Cannabis and cannabinoid research · 2021Review
- Dietary Supplement Use and Its Micronutrient Contribution During Pregnancy and Lactation in the United States.Obstetrics and gynecology · 2020Article
- Current regulatory guidelines and resources to support research of dietary supplements in the United States.Critical reviews in food science and nutrition · 2020Review
- Total Usual Micronutrient Intakes Compared to the Dietary Reference Intakes among U.S. Adults by Food Security Status.Nutrients · 2019Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe describe the purpose of the Dietary Supplement Ingredient Database (DSID), the statistical methodology underlying online calculators of analytically verified supplement content estimates, and the application and significance of DSID label adjustments in nutritional epidemiology. BACKGROUND AND HISTORY: During dietary supplement (DS) manufacturing, many ingredients are added at higher than declared label amounts, but overages are not standardized among manufacturers. As a result, researchers may underestimate nutrient intakes from DSs. The DSID provides statistical tools on the basis of the results of chemical analysis to convert label claims into analytically predicted ingredient amounts. These adjustments to labels are linked to DS products reported in NHANES. RATIONALE: Tables summarizing the numbers of NHANES DS products with ingredient overages and below label content show the importance of DSID adjustments to labels for accurate intake calculations. RECENT DEVELOPMENTS: We show the differences between analytically based estimates and labeled content for vitamin D, calcium, iodine, caffeine, and omega-3 (n-3) fatty acids and their potential impact on the accuracy of intake assessments in large surveys. Analytical overages >20% of label levels are predicted for several nutrients in 50-99% of multivitamin-mineral products (MVMs) reported in NHANES: for iodine and selenium in adult MVMs, for iodine and vitamins D and E in children's MVMs, and for iodine, chromium, and potassium in nonprescription prenatal MVMs. Predicted overages of 10-20% for calcium can be applied to most MVMs and overages >10% for folic acid in the vast majority of adult and children's MVMs. FUTURE DIRECTIONS: DSID studies are currently evaluating ingredient levels in prescription prenatal MVMs and levels of constituents in botanical DSs.
conclusionsWe estimate that the majority of MVM products reported in NHANES have significant overages for several ingredients. It is important to account for nonlabeled additional nutrient exposure from DSs to better evaluate nutritional status in the United States.
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