ArticleDermatology (Basel, Switzerland)2020
Cigarette Smoking and the Risk of Cutaneous Melanoma: A Case-Control Study.
Article in Dermatology (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
- Smoking Status and Survival in Patients With Early-Stage Primary Cutaneous Melanoma.JAMA network open · 2024Trial
- Impact of particulate matter exposure on melanoma risk: A multicentre case-control study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025Observational
- Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Association Between Poor Lifestyle Habits and Cutaneous Melanoma Risk: A Mendelian Randomization Study.Clinical, cosmetic and investigational dermatology · 2025Article
- Comparative study of cutaneous malignant melanoma according to anatomical site: plantar versus non-plantar melanoma.Archives of dermatological research · 2024Article
- Bladder Adenocarcinoma in a Constellation of Multiple Site Malignancies: An Unusual Case and Systematic Review.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- A Narrative Review of Current Knowledge on Cutaneous Melanoma.Clinics and practice · 2024Review
- Global Incidence, Mortality, Risk Factors and Trends of Melanoma: A Systematic Analysis of Registries.American journal of clinical dermatology · 2023Article
- Smoking is an Independent Marker of Poor Prognosis in Cutaneous Melanoma.Acta dermato-venereologica · 2023Article
- Review: The Key Factors to Melanomagenesis.Life (Basel, Switzerland) · 2023Review
- Risk of Melanoma in Patients with Basal Cell Carcinoma: A Population-based Cohort Study.Acta dermato-venereologica · 2023Article
- Advances in Relationship Between Alcohol Consumption and Skin Diseases.Clinical, cosmetic and investigational dermatology · 2023Review
- An Updated Algorithm Integrated With Patient Data for the Differentiation of Atypical Nevi From Early Melanomas: the idScore 2021.Dermatology practical & conceptual · 2022Article
- Cigarette Smoking and Estrogen-Related Cancer-Reply.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Article
- Does smoking affect your skin?Postepy dermatologii i alergologii · 2021Review
- Daily Lifestyle and Cutaneous Malignancies.International journal of molecular sciences · 2021Review
- Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePrevious studies regarding cigarette smoking causing a lower risk of melanoma are inconclusive. Here, we re-examined melanoma risk in relation to cigarette smoking in a large, case-control study.
methodsIn total 1,157 patients with melanoma diagnosed between 2003 and 2011 in the Netherlands and 5,595 controls from the Nijmegen Biomedical Study were included. Information concerning smoking habits and known risk factors for melanoma were obtained through self-administered questionnaires. Logistic regression analyses stratified by gender were performed to study the risk of cigarette smoking on melanoma risk, adjusted for age, marital status, highest level of education, skin type, sun vacation, use of solarium, time spent outdoors, and sun protective measures.
resultsAmong men, current and former smokers did not have a higher risk of melanoma compared to never smokers: adjusted odds ratio (OR) = 0.56 (95% confidence interval [CI]: 0.40-0.79) and adjusted OR = 0.50 (95% CI: 0.39-0.64), respectively. With an increasing number of years smoked the risk of melanoma decreased: <20 years: OR = 0.61 (95% CI: 0.46-0.80); 21-40 years: OR = 0.50 (95% CI: 0.37-0.68); >40 years: OR = 0.26 (95% CI: 0.15-0.44). No clear trend was found for the number of cigarettes smoked. Results for females were less clear and not statistically significant (current smoker: adjusted OR = 0.96, 95% CI: 0.74-1.26, former smoker: adjusted OR = 0.89, 95% CI: 0.73-1.08).
conclusionThis study shows a strong inverse association between cigarette smoking and melanoma risk in men. Fundamental laboratory research is necessary to investigate the biological relation between smoking cigarettes and melanoma.
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