ArticleNeuroImage2019
Heterogeneous profiles of coupled sleep oscillations in human hippocampus.
Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- The effect of zolpidem on targeted memory reactivation during sleep.Learning & memory (Cold Spring Harbor, N.Y.) · 2021Trial
- A-phase Occurrence During Sleep in the Deep Brain Recordings: Multiscale-Entropy and Multiscale-DFA Analysis.Brain topography · 2026Article
- Article
- Surrogates of glymphatic metrics decline and coupled sleep rhythms disruption in Alzheimer's disease.Alzheimer's research & therapy · 2026Article
- Slow-wave sleep and REM sleep differentially contribute to memory representational transformation.Communications biology · 2025Article
- Convolutional Neural Networks for the segmentation of hippocampal structures in postmortem MRI scans.Journal of neuroscience methods · 2025Article
- Coordinated NREM sleep oscillations among hippocampal subfields modulate synaptic plasticity in humans.Communications biology · 2024Article
- Spindle-locked ripples mediate memory reactivation during human NREM sleep.Nature communications · 2024Article
- Memory ability and retention performance relate differentially to sleep depth and spindle type.iScience · 2023Article
- Brain Microtubule Electrical Oscillations-Empirical Mode Decomposition Analysis.Cellular and molecular neurobiology · 2023Article
- Article
- Recurrent Hippocampo-neocortical sleep-state divergence in humans.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Neuromodulation in Beta-Band Power Between Movement Execution and Inhibition in the Human Hippocampus.Neuromodulation : journal of the International Neuromodulation Society · 2022Article
- The Rise and Fall of Slow Wave Tides: Vacillations in Coupled Slow Wave/Spindle Pairing Shift the Composition of Slow Wave Activity in Accordance With Depth of Sleep.Frontiers in neuroscience · 2022Article
- Memory and Sleep: How Sleep Cognition Can Change the Waking Mind for the Better.Annual review of psychology · 2021Article
- Article
- Phase-based coordination of hippocampal and neocortical oscillations during human sleep.Communications biology · 2020Article
- Predicting Grating Orientations With Cross-Frequency Coupling and Least Absolute Shrinkage and Selection Operator in V1 and V4 of Rhesus Monkeys.Frontiers in computational neuroscience · 2020Article
- Sharp Wave-Ripples in Human Amygdala and Their Coordination with Hippocampus during NREM Sleep.Cerebral cortex communications · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Cross-frequency coupling of sleep oscillations is thought to mediate memory consolidation. While the hippocampus is deemed central to this process, detailed knowledge of which oscillatory rhythms interact in the sleeping human hippocampus is lacking. Combining intracranial hippocampal and non-invasive electroencephalography from twelve neurosurgical patients, we characterized spectral power and coupling during non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. Hippocampal coupling was extensive, with the majority of channels expressing spectral interactions. NREM consistently showed delta-ripple coupling, but ripples were also modulated by slow oscillations (SOs) and sleep spindles. SO-delta and SO-theta coupling, as well as interactions between delta/theta and spindle/beta frequencies also occurred. During REM, limited interactions between delta/theta and beta frequencies emerged. Moreover, oscillatory organization differed substantially between i) hippocampus and scalp, ii) sites along the anterior-posterior hippocampal axis, and iii) individuals. Overall, these results extend and refine our understanding of hippocampal sleep oscillations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.