Evidence map›Paper›PMID 31505053›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2020

Neonatal clinical blood sampling led to major blood loss and was associated with bronchopulmonary dysplasia.

William Hellström, Linnéa Forssell, Eva Morsing, Karin Sävman, David Ley

Open access · hybridAbstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Correlation of Transcutaneous pCOPediatric pulmonology · 2026
    Article
  3. A CBC drawn postnatally from umbilical cord blood can provide valuable diagnostic information for infants admitted to the NICU.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Fetal haemoglobin and oxygen requirement in preterm infants: an observational study.Archives of disease in childhood. Fetal and neonatal edition · 2025
    Observational
  13. Tiny baby math: supralinear implications for management of infants born at less than 24 weeks gestation.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

William HellströmDepartment of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-6669-260X
Linnéa ForssellDepartment of Clinical Sciences Lund, Paediatrics, Lund University, Skåne University Hospital, Lund, Sweden.
Eva MorsingDepartment of Clinical Sciences Lund, Paediatrics, Lund University, Skåne University Hospital, Lund, Sweden.
Karin SävmanDepartment of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
David LeyDepartment of Clinical Sciences Lund, Paediatrics, Lund University, Skåne University Hospital, Lund, Sweden.
Lund University · SESahlgrenska University Hospital · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimStudies indicate that reduced foetal haemoglobin levels are related to increased neonatal morbidity rates. This study investigated the relationships between sampling-related blood loss and adult blood transfusions administered during postnatal days 1-14 and the development of severe neonatal morbidities in extremely preterm infants born before 28 weeks of gestation.

methodsThe medical files of 149 extremely preterm infants born at two university hospitals in Sweden from 2013 to 2018 were investigated.

resultsBlood sampling resulted in a 58% depletion of the endogenous blood volume postnatal days 1-14 (median 40.4 mL/kg, interquartile range 23.9-53.3 mL/kg) and correlated with the adult erythrocyte transfusion volume (r

conclusionDiagnostic blood sampling led to major endogenous blood loss replaced with adult blood components and was associated with the development of BPD.

Indexed as

Bronchopulmonary DysplasiaEnterocolitis, NecrotizingAdultGestational AgeHumansInfantInfant, Extremely PrematureInfant, NewbornSwedenanaemiablood samplingbronchopulmonary dysplasiaextremely pretermtransfusion

Identifiers

PMID31505053
PMCPMC7155086
OpenAlexW2972690629

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.