Evidence map›Paper›PMID 31504952›Full record

ArticlePhysical therapy2019

Predicting Improved Daily Use of the More Affected Arm Poststroke Following Constraint-Induced Movement Therapy.

Mohammad H Rafiei, Kristina M Kelly, Alexandra L Borstad, Hojjat Adeli, Lynne V Gauthier

Open access · greenAbstract read
In one paragraph

Article in Physical therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Mohammad H RafieiWhiting School of Engineering, Johns Hopkins University, Baltimore, Maryland.
Kristina M KellyDepartment of Neurology, The Ohio State University, Columbus, Ohio.
Alexandra L BorstadDepartment of Physical Therapy, The College of St Scholastica, Duluth, Minnesota.
Hojjat AdeliDepartment of Biomedical Informatics, Department of Neurology, Department of Neuroscience, The Ohio State University.
Lynne V GauthierDepartment of Physical Therapy and Kinesiology, University of Massachusetts Lowell, 3 Solomon Way, Weed Hall 218D, Lowell, MA 01854 (USA).
The Ohio State University · USCollege of St. Scholastica · USJohns Hopkins University · USUniversity of Massachusetts Lowell · US

Funding

The Ohio State University Center for Clinical and Translational Science (UL1)UL1TR000090 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2012 to 2013
$7.9M
NCATS NIH HHS UL1 TR000090
6 · The paper itself

Abstract

backgroundConstraint-induced movement therapy (CI therapy) produces, on average, large and clinically meaningful improvements in the daily use of a more affected upper extremity in individuals with hemiparesis. However, individual responses vary widely.

objectiveThe study objective was to investigate the extent to which individual characteristics before treatment predict improved use of the more affected arm following CI therapy.

designThis study was a retrospective analysis of 47 people who had chronic (> 6 months) mild to moderate upper extremity hemiparesis and were consecutively enrolled in 2 CI therapy randomized controlled trials.

methodsAn enhanced probabilistic neural network model predicted whether individuals showed a low, medium, or high response to CI therapy, as measured with the Motor Activity Log, on the basis of the following baseline assessments: Wolf Motor Function Test, Semmes-Weinstein Monofilament Test of touch threshold, Motor Activity Log, and Montreal Cognitive Assessment. Then, a neural dynamic classification algorithm was applied to improve prognostic accuracy using the most accurate combination obtained in the previous step.

resultsMotor ability and tactile sense predicted improvement in arm use for daily activities following intensive upper extremity rehabilitation with an accuracy of nearly 100%. Complex patterns of interaction among these predictors were observed. LIMITATIONS: The fact that this study was a retrospective analysis with a moderate sample size was a limitation.

conclusionsAdvanced machine learning/classification algorithms produce more accurate personalized predictions of rehabilitation outcomes than commonly used general linear models.

Indexed as

MovementStroke RehabilitationActivities of Daily LivingAlgorithmsArmExercise TherapyFemaleHumansMaleMiddle AgedMotor ActivityNeural Networks, ComputerParesisPrognosisRetrospective StudiesSensitivity and Specificity

Identifiers

PMID31504952
PMCPMC7105113
OpenAlexW2972300160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.