Evidence map›Paper›PMID 31504802›Full record

GuidelineNeuro-oncology2020

EANO guideline on the diagnosis and treatment of vestibular schwannoma.

Roland Goldbrunner, Michael Weller, Jean Regis, Morten Lund-Johansen, Pantelis Stavrinou, David Reuss, D Gareth Evans, Florence Lefranc, Kita Sallabanda, Andrea Falini and 5 more

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Neuro-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 219 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
219citing papers in PubMed, 19 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

219 citing papers in PubMed, 19 syntheses or guidelines pooled it, 416 citations in OpenAlex.

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  8. A systematic evaluation of clinical practice guidelines for the treatment and management of vestibular schwannoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  13. Prevalence and patterns of cerebral venous sinus thrombosis following vestibular schwannoma surgery: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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  14. Hearing preservation surgery for vestibular schwannoma: a systematic review and meta-analysis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2024
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  20. Trial

159 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 8 countries.

Roland GoldbrunnerCenter of Neurosurgery, Department of General Neurosurgery, University of Cologne, Cologne, Germany.
Michael WellerDepartment of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
Jean RegisDepartment of Functional and Stereotactic Neurosurgery and Radiosurgery, Timone University Hospital, Marseille, France.
Morten Lund-JohansenDepartment of Neurosurgery, Bergen University Hospital and Department of Clinical Medicine, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway.
Pantelis StavrinouCenter of Neurosurgery, Department of General Neurosurgery, University of Cologne, Cologne, Germany.
David ReussDepartment of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.
D Gareth EvansManchester Centre for Genomic Medicine and NW Laboratory Genetics Hub, Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Florence LefrancDepartment of Neurosurgery, Erasmus Hospital, Free University of Brussels, Brussels, Belgium.
Kita SallabandaDepartment of Neurosurgery, University Hospital San Carlos, Complutense University of Madrid, Madrid, Spain; University Hospital San Carlos, CyberKnife Centre, Genesiscare Madrid, Madrid, Spain.
Andrea FaliniDepartment of Neuroradiology, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy.
Patrick AxonCambridge Skull Base Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Olivier SterkersDepartment of Otolaryngology, Unit of Otology, Auditory implants and Skull Base Surgery, Public Assistance-Paris Hospital, Pitié-Salpêtrière Group Hospital, Paris, France.
Laura FariselliUnit of Radiotherapy, Neurological Institute Carlo Best, Milan, Italy.
Wolfgang WickNeurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.
Joerg-Christian TonnDepartment of Neurosurgery Ludwig-Maximilians University and DKTK partner site, University of Munich, Munich, Germany.
Heidelberg University · DEUniversity of Cologne · DECambridge University Hospitals NHS Foundation Trust · GBErasmus Hospital · BEFondazione IRCCS Istituto Neurologico Carlo Besta · ITLudwig-Maximilians-Universität München · DESorbonne Université · FRUniversidad Complutense de Madrid · ESUniversity of Bergen · NOUniversity of Manchester · GBUniversity of Zurich · CHVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The level of evidence to provide treatment recommendations for vestibular schwannoma is low compared with other intracranial neoplasms. Therefore, the vestibular schwannoma task force of the European Association of Neuro-Oncology assessed the data available in the literature and composed a set of recommendations for health care professionals. The radiological diagnosis of vestibular schwannoma is made by magnetic resonance imaging. Histological verification of the diagnosis is not always required. Current treatment options include observation, surgical resection, fractionated radiotherapy, and radiosurgery. The choice of treatment depends on clinical presentation, tumor size, and expertise of the treating center. In small tumors, observation has to be weighed against radiosurgery, in large tumors surgical decompression is mandatory, potentially followed by fractionated radiotherapy or radiosurgery. Except for bevacizumab in neurofibromatosis type 2, there is no role for pharmacotherapy.

Indexed as

HumansNeuroma, Acousticdiagnosisradiotherapysurgerytreatmentvestibular schwannoma

Identifiers

PMID31504802
PMCPMC6954440
OpenAlexW2970929853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.