Evidence map›Paper›PMID 31504710›Full record

ArticleThe Journal of nutrition2020

Food Insecurity May Be an Independent Risk Factor Associated with Nonalcoholic Fatty Liver Disease among Low-Income Adults in the United States.

Ilya Golovaty, Phyllis C Tien, Jennifer C Price, Lila Sheira, Hilary Seligman, Sheri D Weiser

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
20.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07090083 recruitingnot on this mapstarted 2025, after this paper: background citation

Pediatric MASLD and Food Insecurity

Typeobservational_patient_registrySponsorUniversity of California, San FranciscoRan2025 to 2026Enrolled160ConditionsMASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Food Insecurity
NCT07091539 narecruitingnot on this mapstarted 2025, after this paper: background citation

Food Insecurity and MASLD: A Fruit and Vegetable Intervention Study

TypeinterventionalSponsorUniversity of California, San FranciscoRan2025 to 2027Enrolled48ConditionsMASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Food Insecurity Among ChildrenArmsFruit/vegetable vouchers
3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 130 citations in OpenAlex.

  1. Pooled it
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  10. Socioeconomic Factors and Their Role in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Comprehensive Review.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Review
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  18. Food Insecurity Is Highly Prevalent Amongst Patients With Chronic Liver Disease in Northern England: A Cross-Sectional Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Article
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ilya GolovatyDivision of General Internal Medicine, University of California, San Francisco, San Francisco, CA, USA.
Phyllis C TienDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Jennifer C PriceDivision of Gastroenterology, University of California, San Francisco, San Francisco, CA, USA.
Lila SheiraDivision of HIV, Infectious Disease and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
Hilary SeligmanDepartments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Sheri D WeiserDivision of HIV, Infectious Disease and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USSan Francisco VA Medical Center · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KENNETH E. COVINSKY, MICHAEL A. STEINMAN · 2013 to 2026
$19.9M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Mentoring in Patient Oriented Research on Food Insecurity, HIV and AgingK24AI134326 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHERI Dawn WEISER · 2017 to 2026
$1.4M
NIAID NIH HHS K24 AI134326NIA NIH HHS P30 AG044281NIDDK NIH HHS P30 DK092924NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

backgroundNonalcoholic fatty liver disease (NAFLD), considered a "barometer" of metabolic health, is the leading cause of liver disease in the United States. Despite established associations between food insecurity and obesity, hypertension, and diabetes, little is known about the relation between food insecurity and NAFLD.

objectiveWe sought to evaluate the association of food insecurity with NAFLD among low-income adults in the United States.

methodsWe conducted a cross-sectional analysis of a nationally representative sample of adults from the NHANES (2005-2014 waves). Participants included adults in low-income households (≤200% of the federal poverty level) without chronic viral hepatitis or self-reported heavy alcohol use. Food insecurity was measured using the Household Food Security Survey. Our primary outcome was NAFLD, as estimated by the US Fatty Liver Index, and our secondary outcome was advanced fibrosis, as estimated by the NAFLD fibrosis score. The association between food insecurity (defined as low and very low food security) and hepatic outcomes was assessed using multivariable logistic regression, adjusting for sociodemographic factors.

resultsAmong 2627 adults included in the analysis, 29% (95% CI: 26%, 32%) were food insecure. The median age was 43 y, 58% were female, and 54% were white. The weighted estimated prevalence of NAFLD did not differ significantly by food security status (food secure 31% compared with food insecure 34%, P = 0.21). In the multivariable model, food-insecure adults were more likely to have NAFLD (adjusted OR: 1.38; 95% CI: 1.08, 1.77) and advanced fibrosis (adjusted OR: 2.20; 95% CI: 1.27, 3.82) compared with food-secure adults.

conclusionsFood insecurity may be independently associated with NAFLD and advanced fibrosis among low-income adults in the United States. Future strategies should assess whether improved food access, quality, and healthy eating habits will decrease the growing burden of NAFLD-associated morbidity and mortality among at-risk adults.

Indexed as

Food SupplyPovertyAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseNutrition SurveysRisk FactorsUnited StatesYoung Adultdisparitiesfood insecuritynutritionunderserved populationsurban healthvulnerable populations

Identifiers

PMID31504710
PMCPMC6946902
OpenAlexW2972878688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.