Evidence map›Paper›PMID 31504673›Full record

ArticleThe Journal of nutrition2020

Sodium Intake during Pregnancy, but Not Other Diet Recommendations Aimed at Preventing Cardiovascular Disease, Is Positively Related to Risk of Hypertensive Disorders of Pregnancy.

Mariel Arvizu, Anne A Bjerregaard, Marie T B Madsen, Charlotta Granström, Thorhallur I Halldorsson, Sjurdur F Olsen, Audrey J Gaskins, Janet W Rich-Edwards, Bernard A Rosner, Jorge E Chavarro

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in The Journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Hypertension Management in Pregnancy and Postpartum.Journal of the American Society of Nephrology : JASN · 2026
    Review
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  15. Systematic review and meta-analysis of nutritional interventions to prevent of gestational hypertension or/and preeclampsia among healthy pregnant women.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023
    Review
  16. Article
  17. Non-Specific Low Back Pain, Dietary Salt Intake, and Posterior Lumbar Subcutaneous Edema.International journal of environmental research and public health · 2022
    Article
  18. Article
  19. Dietary factors that affect the risk of pre-eclampsia.BMJ nutrition, prevention & health · 2022
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Mariel ArvizuDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Anne A BjerregaardCentre for Fetal Programming, Statens Serum Institut, Copenhagen, Denmark.
Marie T B MadsenCentre for Fetal Programming, Statens Serum Institut, Copenhagen, Denmark.
Charlotta GranströmCentre for Fetal Programming, Statens Serum Institut, Copenhagen, Denmark.
Thorhallur I HalldorssonCentre for Fetal Programming, Statens Serum Institut, Copenhagen, Denmark.
Sjurdur F OlsenDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Audrey J GaskinsDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Janet W Rich-EdwardsChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Bernard A RosnerChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Jorge E ChavarroDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Statens Serum Institut · DKBrigham and Women's Hospital · USHarvard University · US

Funding

Maternal Exposure to Air Pollution and Early Pregnancy OutcomesR00ES026648 · NIEHS · EMORY UNIVERSITY · PI GASKINS, AUDREY JANE · 2019 to 2021
$730k
Maternal Exposure to Air Pollution and Early Pregnancy OutcomesK99ES026648 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI GASKINS, AUDREY JANE · 2017 to 2018
$246k
NIEHS NIH HHS K99 ES026648NIEHS NIH HHS R00 ES026648
6 · The paper itself

Abstract

backgroundThe role of diet on hypertensive disorders of pregnancy (HDPs), including preeclampsia and gestational hypertension (GHTN), remains unclear.

objectivesWe evaluated whether adherence during pregnancy to dietary recommendations that reduce cardiovascular disease (CVD) in the general population is related to the risk of HDPs.

methodsWe followed 66,651 singleton pregnancies from 62,774 women participating in the Danish National Birth Cohort. Diet was assessed during week of gestation 25 with an FFQ from which we created 2 dietary pattern scores: 1) AHA, based on the diet recommendations from the AHA 2020 Strategic Impact Goals; and 2) the Dietary Approaches to Stop Hypertension (DASH) diet. Cases of HDPs were identified through linkage with the Danish National Patient Registry. RRs and 95% CIs of HDPs were estimated by increasing quintiles of adherence to the AHA and DASH scores using log-Poisson regression models with generalized estimating equations-to account for repeated pregnancies per woman-while adjusting for potential confounders.

resultsWe identified 1809 cases of HDPs: n = 1310 preeclampsia (n = 300 severe preeclampsia) and n = 499 cases of GHTN. Greater adherence to AHA or DASH scores was not related to the risk of HDPs. However, when each component of the scores was separately evaluated, there were positive linear relations of sodium intake with HDPs (P-linearity < 0.01). Women with the highest sodium intake [median 3.70 g/d (range: 3.52, 7.52 g/d)] had 54% (95% CI:16%, 104%) higher risk of GHTN and 20% (95% CI:1%, 42%) higher risk of preeclampsia than women with the lowest intake [median 2.60 g/d (range: 0.83, 2.79 g/d)]. In addition, intake of whole grains was positively related to the risk of GHTN but not to preeclampsia ( P-heterogeneity = 0.002).

conclusionSodium intake during pregnancy, but no other diet recommendations to prevent CVD among nonpregnant adults, is positively related to the occurrence of HDPs among pregnant Danish women.

Indexed as

DietAdultCardiovascular DiseasesFemaleHumansHypertension, Pregnancy-InducedPre-EclampsiaPregnancySodium, DietarySodium, DietaryAHA 2020 goalsDASHdietary patternsgestational hypertensionpreeclampsiapregnancysodium

Identifiers

PMID31504673
PMCPMC6946899
OpenAlexW2971237373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.