ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2019
Out-of-hospital cardiac arrest due to idiopathic ventricular fibrillation in patients with normal electrocardiograms: results from a multicentre long-term registry.
Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Diagnosis and management of very rare primary arrhythmia syndromes in children and adults: a Clinical Consensus Statement of the European Heart Rhythm Association of the ESC and the Association of Cardiovascular Nursing & Allied Professions of the ESC, endorsed by the Association for European Paediatric and Congenital Cardiology.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Guideline
- Cardiac MRI after Sudden Cardiac Arrest: A Systematic Review.Radiology. Cardiothoracic imaging · 2024Pooled it
- 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families.Heart rhythm · 2021Guideline
- Clinical manifestations and outcomes of idiopathic ventricular fibrillation and early repolarization syndrome in adolescents: A multicenter cohort study.Heart rhythm O2 · 2026Article
- Reevaluation of ECGs of a German non coronary sudden cardiac arrest cohort.Scientific reports · 2026Article
- Management of recurrent idiopathic ventricular fibrillation: a case report from diagnosis to successful ablation.European heart journal. Case reports · 2025Article
- Diagnostic, pharmacological, and ablation approaches for idiopathic ventricular fibrillation: the 2024 European Heart Rhythm Association survey.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Idiopathic Ventricular Fibrillation: Substrates, Mechanisms and Treatment.Arrhythmia & electrophysiology review · 2025Review
- Idiopathic Ventricular Fibrillation - Just How Much Idiopathic is it?Reviews in cardiovascular medicine · 2024Review
- The Dutch Idiopathic Ventricular Fibrillation Registry: progress report on the quest to identify the unidentifiable.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024Article
- Catheter ablation in a geriatric case presenting idiopathic ventricular fibrillation initiated by Purkinje-related premature ventricular contractions.HeartRhythm case reports · 2024Article
- The Mystery of Electrical Storm: A Case Report.Cureus · 2024Article
- Surviving the Shocks: A Contemporary of Short-coupled Ventricular Fibrillation.The Journal of innovations in cardiac rhythm management · 2024Article
- Outcome of patients with idiopathic ventricular fibrillation and correlation with ECG markers of early repolarization.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Article
- The genetic basis of apparently idiopathic ventricular fibrillation: a retrospective overview.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Identification of concealed cardiomyopathy using next-generation sequencing-based genetic testing in Korean patients initially diagnosed with idiopathic ventricular fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- NovelExperimental and therapeutic medicine · 2023Article
- Trigger and Substrate Mapping and Ablation for Ventricular Fibrillation in the Structurally Normal Heart.Journal of cardiovascular development and disease · 2023Review
- Explaining the Unexplained: A Practical Approach to Investigating the Cardiac Arrest Survivor.Arrhythmia & electrophysiology review · 2023Review
- State-of-the-Art Multimodality Imaging in Sudden Cardiac Arrest with Focus on Idiopathic Ventricular Fibrillation: A Review.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
51 authors at 20 institutions in 11 countries.
Funding
Abstract
aimsTo define the clinical characteristics and long-term clinical outcomes of a large cohort of patients with idiopathic ventricular fibrillation (IVF) and normal 12-lead electrocardiograms (ECGs). METHODS AND
resultsPatients with ventricular fibrillation as the presenting rhythm, normal baseline, and follow-up ECGs with no signs of cardiac channelopathy including early repolarization or atrioventricular conduction abnormalities, and without structural heart disease were included in a registry. A total of 245 patients (median age: 38 years; males 59%) were recruited from 25 centres. An implantable cardioverter-defibrillator (ICD) was implanted in 226 patients (92%), while 18 patients (8%) were treated with drug therapy only. Over a median follow-up of 63 months (interquartile range: 25-110 months), 12 patients died (5%); in four of them (1.6%) the lethal event was of cardiac origin. Patients treated with antiarrhythmic drugs only had a higher rate of cardiovascular death compared to patients who received an ICD (16% vs. 0.4%, P = 0.001). Fifty-two patients (21%) experienced an arrhythmic recurrence. Age ≤16 years at the time of the first ventricular arrhythmia was the only predictor of arrhythmic recurrence on multivariable analysis [hazard ratio (HR) 0.41, 95% confidence interval (CI) 0.18-0.92; P = 0.03].
conclusionPatients with IVF and persistently normal ECGs frequently have arrhythmic recurrences, but a good prognosis when treated with an ICD. Children are a category of IVF patients at higher risk of arrhythmic recurrences.
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