Evidence map›Paper›PMID 31504416›Full record

ArticleEuropean heart journal2019

Mortality reduction with physical activity in patients with and without cardiovascular disease.

Sang-Woo Jeong, Sun-Hwa Kim, Si-Hyuck Kang, Hee-Jun Kim, Chang-Hwan Yoon, Tae-Jin Youn, In-Ho Chae

Abstract read
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In one paragraph

Article in European heart journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 176 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
176citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

176 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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116 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Sang-Woo JeongDepartment of Internal Medicine, Cardiovascular Center, Seoul National University, Bundang Hospital, 82, Gumi-Ro 173 Beon-Gil, Bundang-Gu, Gyeonggi-Do, Seongnam-Si, Korea.
Sun-Hwa KimDepartment of Internal Medicine, Cardiovascular Center, Seoul National University, Bundang Hospital, 82, Gumi-Ro 173 Beon-Gil, Bundang-Gu, Gyeonggi-Do, Seongnam-Si, Korea.
Si-Hyuck KangDepartment of Internal Medicine, Cardiovascular Center, Seoul National University, Bundang Hospital, 82, Gumi-Ro 173 Beon-Gil, Bundang-Gu, Gyeonggi-Do, Seongnam-Si, Korea.
Hee-Jun KimDepartment of Internal Medicine, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul, Korea.
Chang-Hwan YoonDepartment of Internal Medicine, Cardiovascular Center, Seoul National University, Bundang Hospital, 82, Gumi-Ro 173 Beon-Gil, Bundang-Gu, Gyeonggi-Do, Seongnam-Si, Korea.
Tae-Jin YounDepartment of Internal Medicine, Cardiovascular Center, Seoul National University, Bundang Hospital, 82, Gumi-Ro 173 Beon-Gil, Bundang-Gu, Gyeonggi-Do, Seongnam-Si, Korea.
In-Ho ChaeDepartment of Internal Medicine, Cardiovascular Center, Seoul National University, Bundang Hospital, 82, Gumi-Ro 173 Beon-Gil, Bundang-Gu, Gyeonggi-Do, Seongnam-Si, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsPhysical activity has been shown to reduce mortality in a dose-response fashion. Current guidelines recommend 500-1000 metabolic equivalent task (MET)-min per week of regular physical activity. This study aimed to compare the impact of leisure-time physical activity on mortality in primary versus secondary cardiovascular prevention. METHODS AND

resultsThis study included a total of 131 558 and 310 240 subjects with and without cardiovascular disease (CVD), respectively, from a population-based cohort. Leisure-time physical activity was measured by self-report questionnaires. The study subjects were followed-up for a median of 5.9 years, and the main study outcome was all-cause mortality. There was an inverse relationship between the physical activity level and the mortality risk in both groups. The benefit in the secondary prevention group was shown to be greater than that in the primary prevention group: every 500 MET-min/week increase in physical activity resulted in a 14% and 7% risk reduction in mortality in the secondary and primary prevention groups, respectively (interaction P < 0.001). In addition, while individuals without CVD benefited the most between 1 and 500 MET-min/week of physical activity, the benefit in those with CVD continued above 500 - 1000 MET-min/week. The adjusted mortality risk of individuals with CVD who performed a high level of physical activity (≥1000 MET-min/week) was shown to be comparable to or lower than that of their counterparts without CVD.

conclusionIndividuals with CVD may benefit from physical activity to a greater extent than do healthy subjects without CVD.

Indexed as

ExerciseHealth BehaviorLeisure ActivitiesPrimary PreventionSecondary PreventionAdultAgedAged, 80 and overCardiovascular DiseasesCase-Control StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedProtective FactorsCohort studyExerciseMetabolic equivalentPhysical activityRisk reduction behaviourSecondary prevention

Identifiers

PMID31504416
PMCPMC6855138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.