Evidence map›Paper›PMID 31504233›Full record

ReviewBritish medical bulletin2019

Ethical and policy issues raised by uterus transplants.

Laura O'Donovan, Nicola Jane Williams, Stephen Wilkinson

Erratum issuedAbstract readReview
In one paragraph

Review in British medical bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Uterus transplantation: an ethical analysis.Wiener medizinische Wochenschrift (1946) · 2026
    Review
  2. Review
  3. Risks of uterus transplantation: a scoping review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Article
  4. New Frontiers in Reproductive Health: Australians' Support for Uterus Transplantation.The Australian & New Zealand journal of obstetrics & gynaecology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Uterus Transplantation as a Surgical Innovation.Journal of bioethical inquiry · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Ethical issues in uterine transplantation.Korean journal of transplantation · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Laura O'DonovanDepartment of Politics, Philosophy, & Religion, County South, Lancaster University, Lancaster, LA1 4YQ, United Kingdom.
Nicola Jane WilliamsDepartment of Politics, Philosophy, & Religion, County South, Lancaster University, Lancaster, LA1 4YQ, United Kingdom.
Stephen WilkinsonDepartment of Politics, Philosophy, & Religion, County South, Lancaster University, Lancaster, LA1 4YQ, United Kingdom.

Funding

Wellcome Trust 097897/Z/11/Z
6 · The paper itself

Abstract

introductionIn 2014, Brännström and colleagues reported the first human live birth following uterine transplantation (UTx). Research into this treatment for absolute uterine factor infertility has since grown with clinical trials currently taking place across centers in at least thirteen countries worldwide. SOURCES OF DATA: This review summarizes and critiques the academic literature on ethical and policy issues raised by UTx. AREAS OF AGREEMENT: There is general agreement on the importance of risk reduction and, in principle, to the sharing and maintenance of patient data on an international registry. AREAS OF CONTROVERSY: There are numerous areas of controversy ranging from whether it is ethically justified to carry out uterus transplants at all (considering the associated health risks) to how deceased donor organs for transplant should be allocated. This review focuses on three key issues: the choice between deceased and living donors, ensuring valid consent to the procedure and access to treatment. GROWING POINTS: UTx is presently a novel and rare procedure but is likely to become more commonplace in the foreseeable future, given the large number of surgical teams working on it worldwide. AREAS TIMELY FOR DEVELOPING RESEARCH: Uterus transplantation requires us to re-examine fundamental questions about the ethical and social value of gestation. If eventually extended to transgender women or even to men, it may also require us to reconceptualize what it is to be a 'father' or to be a 'mother', and the definition of these terms in law.

Indexed as

Ethics, MedicalFamily CharacteristicsFemaleHealth PolicyHumansInfertility, FemaleLiving DonorsUterusaccess to treatmentAUFIconsentdonorsethicsfundinginfertilityreproductiontransplantationuterus

Identifiers

PMID31504233
PMCPMC6821981

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.