ArticleThe American journal of clinical nutrition2019
Total energy expenditure measured using doubly labeled water compared with estimated energy requirements in older adults (≥65 y): analysis of primary data.
Article in The American journal of clinical nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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14 citing papers in PubMed, 33 citations in OpenAlex.
- Association between fish-related metabolites and metabolic syndrome risk factors in Japan: INTERLIPID metabolome -wide association study.European journal of nutrition · 2026Observational
- Investigating the impact of body composition on the estimation of resting metabolic rate: new equations for adults aged ≥65 years developed using cross-sectional data.The American journal of clinical nutrition · 2025Article
- Exploring the physiological factors relating to energy balance in women with polycystic ovary syndrome: a scoping review.Nutrition reviews · 2025Article
- A small switch in perspective: Comparing weight loss by nutrient balance versus caloric balance.Biology of sport · 2024Article
- Development and validation of age-specific predictive equations for total energy expenditure and physical activity levels for older adults.The American journal of clinical nutrition · 2024Article
- Higher baseline resting metabolic rate is associated with 1-year frailty decline among older adults residing in an urban area.BMC geriatrics · 2023Article
- A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 2: physiological measurements.European journal of applied physiology · 2023Review
- Development and validation of new predictive equations for the resting metabolic rate of older adults aged ≥65 y.The American journal of clinical nutrition · 2023Article
- The Association of Predicted Resting Energy Expenditure with Risk of Breast Cancer among Postmenopausal Women in the Women's Health Initiative Cohort.Cancer prevention research (Philadelphia, Pa.) · 2022Article
- External validation of BIA equations to estimate appendicular skeletal muscle mass in older adults: Importance of the bias analysis and derivation of correction factors to achieve agreement.Frontiers in nutrition · 2022Article
- A new doubly labelled water anthropometry-based equation for prediction of total daily energy expenditure in older people from low- and middle-income countries.European journal of clinical nutrition · 2021Article
- Total Energy Expenditure and Functional Status in Older Adults: A Doubly Labelled Water Study.The journal of nutrition, health & aging · 2021Article
- Estimating total daily energy requirements in community-dwelling older adults: validity of previous predictive equations and modeling of a new approach.European journal of clinical nutrition · 2021Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundContemporary energy expenditure data are crucial to inform and guide nutrition policy in older adults to optimize nutrition and health.
objectiveThe aim was to determine the optimal method of estimating total energy expenditure (TEE) in adults (aged ≥65 y) through 1) establishing which published predictive equations have the closest agreement between measured resting metabolic rate (RMR) and predicted RMR and 2) utilizing the RMR equations with the best agreement to predict TEE against the reference method of doubly labeled water (DLW).
methodsA database consisting of international participant-level TEE data from DLW studies was developed to enable comparison with energy requirements estimated by 17 commonly used predictive equations. This database included 31 studies comprising 988 participant-level RMR data and 1488 participant-level TEE data. Mean physical activity level (PAL) was determined for men (PAL = 1.69, n = 320) and women (PAL = 1.66, n = 668). Bland-Altman plots assessed agreement of measured RMR and TEE with predicted RMR and TEE in adults aged ≥65 y, and subgroups of 65-79 y and ≥80 y. Linear regression assessed proportional bias.
resultsThe Ikeda, Livingston, and Mifflin equations most closely agreed with measured RMR and TEE in all adults aged ≥65 y and in the 65-79 y and ≥80 y subgroups. In adults aged ≥65 y, the Ikeda and Livingston equations overestimated TEE by a mean ± SD of 175 ± 1362 kJ/d and 86 ± 1344 kJ/d, respectively. The Mifflin equation underestimated TEE by a mean ± SD of 24 ± 1401 kJ/d. Proportional bias was present as energy expenditure increased.
conclusionsThe Ikeda, Livingston, or Mifflin equations are recommended for estimating energy requirements of older adults. Future research should focus on developing predictive equations to meet the requirements of the older population with consideration given to body composition and functional measures.
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