Evidence map›Paper›PMID 31503341›Full record

ArticleThe British journal of surgery2020

Trauma models to identify major trauma and mortality in the prehospital setting.

C A Sewalt, E Venema, E J A Wiegers, F E Lecky, S C E Schuit, D den Hartog, E W Steyerberg, H F Lingsma

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in The British journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06740409 (Can the Modified Rapid Emergency Medicine Score), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06740409 completednot on this mapstarted 2025, after this paper: background citation

Can the Modified Rapid Emergency Medicine Score (mREMS) Predict Trauma Patients' Outcomes in a Deteriorated Health System After Decades of Conflict?

TypeobservationalSponsorAl-Nahrain UniversityRan2025 to 2026Enrolled292ConditionsTrauma
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Substantial heterogeneity in trauma triage tool characteristic operationalization for identification of major trauma: a hybrid systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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  5. Assessing and Addressing Model Trustworthiness Trade-offs in Trauma Triage.International journal of artificial intelligence tools : architectures, languages, algorithms · 2024
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  14. A comparison of agreement between actigraphy and polysomnography for assessing sleep during posttraumatic amnesia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

C A SewaltDepartment of Public Health, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0003-3270-4814
E VenemaDepartment of Public Health, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.
E J A WiegersDepartment of Public Health, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.
F E LeckySchool of Health and Related Research, Sheffield University, Salford Royal NHS Foundation Trust, Salford, UK.
S C E SchuitDepartment of Emergency Medicine, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.
D den HartogTrauma Research Unit, Department of Surgery, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.
E W SteyerbergDepartment of Public Health, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.
H F LingsmaDepartment of Public Health, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.
Erasmus MC · NLLeiden University Medical Center · NLSalford Royal NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with major trauma might benefit from treatment in a trauma centre, but early identification of major trauma (Injury Severity Score (ISS) over 15) remains difficult. The aim of this study was to undertake an external validation of existing prognostic models for injured patients to assess their ability to predict mortality and major trauma in the prehospital setting.

methodsPrognostic models were identified through a systematic literature search up to October 2017. Injured patients transported by Emergency Medical Services to an English hospital from the Trauma Audit and Research Network between 2013 and 2016 were included. Outcome measures were major trauma (ISS over 15) and in-hospital mortality. The performance of the models was assessed in terms of discrimination (concordance index, C-statistic) and net benefit to assess the clinical usefulness.

resultsA total of 154 476 patients were included to validate six previously proposed prediction models. Discriminative ability ranged from a C-statistic value of 0·602 (95 per cent c.i. 0·596 to 0·608) for the Mechanism, Glasgow Coma Scale, Age and Arterial Pressure model to 0·793 (0·789 to 0·797) for the modified Rapid Emergency Medicine Score (mREMS) in predicting in-hospital mortality (11 882 patients). Major trauma was identified in 52 818 patients, with discrimination from a C-statistic value of 0·589 (0·586 to 0·592) for mREMS to 0·735 (0·733 to 0·737) for the Kampala Trauma Score in predicting major trauma. None of the prediction models met acceptable undertriage and overtriage rates.

conclusionCurrently available prehospital trauma models perform reasonably in predicting in-hospital mortality, but are inadequate in identifying patients with major trauma. Future research should focus on which patients would benefit from treatment in a major trauma centre.

Indexed as

AdultAgedAged, 80 and overAge FactorsBlood PressureEmergency Medical ServicesFemaleGlasgow Coma ScaleHospital MortalityHumansInjury Severity ScoreMaleMiddle AgedModels, StatisticalPrognosisReproducibility of Results

Identifiers

PMID31503341
PMCPMC7079101
OpenAlexW2972953842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.