Evidence map›Paper›PMID 31503006›Full record

ArticleAging2019

Cognitive efficiency in late midlife is linked to lifestyle characteristics and allostatic load.

Justinas Narbutas, Maxime Van Egroo, Daphne Chylinski, Pamela Villar González, Claudia Garcia Jimenez, Gabriel Besson, Pouya Ghaemmaghami, Grégory Hammad, Vincenzo Muto, Christina Schmidt and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. The Association Between Cardiometabolic Risk and Cognitive Function Among Older Americans and Chinese.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. An Exploratory Study of Correlates of Allostatic Load in Older People Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2020
    Article
  14. Article
  15. Prevalence and Correlates of Mild Cognitive Impairment in Older Outpatients: A Cross-Sectional Study.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Justinas NarbutasGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Maxime Van EgrooGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Daphne ChylinskiGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Pamela Villar GonzálezGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Claudia Garcia JimenezGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Gabriel BessonGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Pouya GhaemmaghamiGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Grégory HammadGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Vincenzo MutoGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Christina SchmidtGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
André LuxenGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Eric SalmonGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Pierre MaquetGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Christine BastinGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Gilles VandewalleGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
Fabienne ColletteGIGA-Institute, Cyclotron Research Centre/In Vivo Imaging, University of Liège, Liège 4000, Belgium.
University of Liège · BECentre Hospitalier Universitaire de Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated whether cognitive fitness in late midlife is associated with physiological and psychological factors linked to increased risk of age-related cognitive decline. Eighty-one healthy late middle-aged participants (mean age: 59.4 y; range: 50-69 y) were included. Cognitive fitness consisted of a composite score known to be sensitive to early subtle cognitive change. Lifestyle factors (referenced below as cognitive reserve factors; CRF) and affective state were determined through questionnaires, and sleep-wake quality was also assessed through actimetry. Allostatic load (AL) was determined through a large range of objective health measures. Generalized linear mixed models, controlling for sex and age, revealed that higher cognitive reserve and lower allostatic load are related to better cognitive efficiency. Crystallized intelligence, sympathetic nervous system functioning and lipid metabolism were the only sub-fields of CRF and AL to be significantly associated with cognition. These results show that previous lifestyle characteristics and current physiological status are simultaneously explaining variability in cognitive abilities in late midlife. Results further encourage early multimodal prevention programs acting on both of these modifiable factors to preserve cognition during the aging process.

Indexed as

AllostasisModels, StatisticalActigraphyAgedCognitive ReserveFemaleHumansLife StyleMaleMiddle AgedSleepagingallostatic loadcognitioncognitive reservemidlife

Identifiers

PMID31503006
PMCPMC6756890
OpenAlexW2973047245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.