Evidence map›Paper›PMID 31502579›Full record

ArticleJournal of biosciences2019

Down-regulation effects of IFN-α on p11, 5-htr1b and 5-HTR4 protein levels were affected by NH

Jiqiang Guo, Huaxia Ding, Zhuangwei Lv, Junna Jiao, Hui Wang, Yanhong Ji

Abstract read
PubMed
In one paragraph

Article in Journal of biosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jiqiang GuoDepartment of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Centre, Xi'an 710061, People's Republic of China.
Huaxia Ding
Zhuangwei Lv
Junna Jiao
Hui Wang
Yanhong Ji
Xinxiang Medical University · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In previous studies, we found interferon-α (IFN-α) could reduce protein levels of p11, 5-hydroxytryptamine receptor 1b (5-HT1b) and 5-hydroxytryptamine receptor 4 (5-HT4), but does not influence their messenger RNA levels in SH-sy5y cells. Thus, we investigated the post-transcriptional modulation of these molecules by IFN-α. SH-sy5y cells were treated with IFN-α, NH

Indexed as

Ammonium ChlorideCell Line, TumorCell-Penetrating PeptidesDepressionGene Expression RegulationHumansInterferon-alphaLeupeptinsLysosomesProteolysisReceptor, Serotonin, 5-HT1BRecombinant ProteinsRNA, MessengerSignal TransductionUbiquitinAmmonium Chloridebenzyloxycarbonylleucyl-leucyl-leucine aldehydeCell-Penetrating PeptidesHTR1B protein, humanInterferon-alphaLeupeptinsp11 peptideReceptor, Serotonin, 5-HT1BRecombinant ProteinsRNA, MessengerUbiquitin

Identifiers

PMID31502579
OpenAlexW2967864124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.