ArticleeLife2019
Processing of different spatial scales in the human brain.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Spatial memory under emotion: Effects across encoding, maintenance and retrieval.British journal of psychology (London, England : 1953) · 2026Article
- Graded encoding of spatial novelty scales in the human brain.Nature communications · 2025Article
- A map of words: Retrieving the spatial layout of medium-scale geographical maps through distributional semantics.Neuropsychologia · 2025Article
- Cognitive maps for hierarchical spaces in the human brain.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Visual imagery of familiar people and places in category selective cortex.Neuroscience of consciousness · 2025Article
- Processing of social closeness in the human brain.Communications biology · 2024Article
- Article
- A neural circuit for spatial orientation derived from brain lesions.Cerebral cortex (New York, N.Y. : 1991) · 2024Review
- Differential involvement of the anterior and posterior hippocampus, parahippocampus, and retrosplenial cortex in making precise judgments of spatial distance and object size for remotely acquired memories of environments and objects.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Scene Perception and Visuospatial Memory Converge at the Anterior Edge of Visually Responsive Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Single voxel autocorrelation uncovers gradients of temporal dynamics in the hippocampus and entorhinal cortex during rest and navigation.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Functional brain connectivity during exposure to the scale and color of interior built environments.Human brain mapping · 2023Article
- Ramp-shaped neural tuning supports graded population-level representation of the object-to-scene continuum.Scientific reports · 2022Article
- The trend of disruption in the functional brain network topology of Alzheimer's disease.Scientific reports · 2022Article
- Predictive Representations in Hippocampal and Prefrontal Hierarchies.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Neural basis of topographical disorientation in the primate posterior cingulate gyrus based on a labeled graph.AIMS neuroscience · 2022Article
- A deeper look at vision and memory.Nature neuroscience · 2022Article
- The human brain uses spatial schemas to represent segmented environments.Current biology : CB · 2021Article
- Brain Coding of Social Network Structure.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Structuring Knowledge with Cognitive Maps and Cognitive Graphs.Trends in cognitive sciences · 2021Review
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4 authors.
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Abstract
Humans navigate across a range of spatial scales, from rooms to continents, but the brain systems underlying spatial cognition are usually investigated only in small-scale environments. Do the same brain systems represent and process larger spaces? Here we asked subjects to compare distances between real-world items at six different spatial scales (room, building, neighborhood, city, country, continent) under functional MRI. Cortical activity showed a gradual progression from small to large scale processing, along three gradients extending anteriorly from the parahippocampal place area (PPA), retrosplenial complex (RSC) and occipital place area (OPA), and along the hippocampus posterior-anterior axis. Each of the cortical gradients overlapped with the visual system posteriorly and the default-mode network (DMN) anteriorly. These results suggest a progression from concrete to abstract processing with increasing spatial scale, and offer a new organizational framework for the brain's spatial system, that may also apply to conceptual spaces beyond the spatial domain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.